Mechanism Of UV-Induced DNA Dewar Lesion Revealed
11/30/2011
Excessive exposure to ultraviolet (UV) radiation of sunlight can result in skin damage and may even induce skin cancers. Irradiation with UV light causes mutations in the DNA, which can interfere with or even inhibit the read-out of genetic information and hence affect the cell function. The Dewar lesion is one of the major UV-induced reaction products, which can itself generate mutations...
Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma (DLBCL), the most aggressive and common type of lymphoma in adults. The new study, published in Nature, reveals the underlying molecular mechanism contributing to the development of lymphomagenesis...
Everolimus Prolongs Progression-Free Survival For Patients With Neuroendocrine Tumors
11/30/2011
Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of carcinoid syndrome, according to researchers at The University of Texas MD Anderson Cancer Center...
Patient Care, Safety, Research Relating To IVC Filters
11/30/2011
Researchers have published the largest single patient population study to date on a method for following patients with retrievable inferior vena cava (IVC) filters - devices used to keep blood clots from traveling to the lungs...
Second Cancer Risk Mainly Confined To Same Type Recurrence
11/29/2011
Worldwide, approximately 15% of cancer survivors are diagnosed with a second primary cancer. A study published in the Canadian Medical Association Journal (CMAJ) reveals that those who have survived cancer are at more than double the risk of a second primary cancer of the same type, but the risk of developing a second cancer of a different type is only marginally higher...
Multiple Myeloma - First Risk Genes Discovered
11/29/2011
According to a paper published online in Nature Genetics, a team of scientists led by The Institute of Cancer Research (ICR) has demonstrated for the first time that a person's genes influence their risk of developing multiple myeloma, a cancer of plasma cells, which is a type of white blood cell responsible for the production of antibodies...
HPV Vaccination Change Is A Good Thing, Says British Dental Health Foundation
11/29/2011
The Government's plan to switch its Human Papilloma Virus (HPV) vaccination from "Cervarix" to Gardasil" from Sep. 2012, has been welcomed by the British Dental Health Foundation. The leading oral health charity believes that the novel vaccine will deliver increased health benefits and prevent genital warts...
In Cancer Survivors, Risk Of Second Cancer Mainly Confined To The Same Cancer Type As The First
11/29/2011
Cancer survivors have more than double the risk of a second primary cancer of the same type, according to a study published in CMAJ (Canadian Medical Association Journal).. Danish researchers looked at data for the entire population of Denmark (7 493 705 people) from 1980 to 2007 to determine whether the risk of secondary cancer is linked to the type of cancer found in the first instance...
Higher Prevalence Of Leukemia, Infections Among The Elderly May Be Explained By Aging Stem Cells
11/29/2011
Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system...
Link Between Breast Cancer Type And Paternal Cancer
11/29/2011
The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT). New research published in BioMed Central's open access journal BMC Cancer looked at the relationship between women with breast cancer and diagnosis of cancer in their parents...