Anti-Inflammatory Polyphenols Discovered In Apple Peels
12/01/2011
Here's another reason why "an apple a day keeps the doctor away" - according to new research findings published in the Journal of Leukocyte Biology*, oral ingestion of apple polyphenols (antioxidants found in apple peels) can suppress T cell activation to prevent colitis in mice...
Genetic Sequencing Could Help Match Patients With Biomarker-Driven Cancer Trials, Treatments
12/01/2011
As cancer researchers continue to identify genetic mutations driving different cancer subtypes, they are also creating a catalog of possible targets for new treatments...
In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients. The effect, in some cases, was profound. The phase I study, published in the Dec...
Potential Link Between Tumor Suppressor Protein Functions And Human Epigenome
12/01/2011
Scientists investigating the interactions, or binding patterns, of a major tumor-suppressor protein known as p53 with the entire genome in normal human cells have turned up key differences from those observed in cancer cells...
Breast Cancer Progression Halted By Gene
12/01/2011
Newly published research explores the role of 14-3-3sigma in tumour suppression New research out of McGill University's Goodman Cancer Research Centre provides compelling new evidence that a gene known as 14-3-3sigma plays a critical role in halting breast cancer initiation and progression. The study, led by the Dept. of Biochemistry's William J...
Potential Link Between Cancer And A Common Chemical In Consumer Products
11/30/2011
A study led by a group of Nanyang Technological University (NTU) researchers has found that a chemical commonly used in consumer products can potentially cause cancer. The chemical, Zinc Oxide, is used to absorb harmful ultra violet light. But when it is turned into nano-sized particles, they are able to enter human cells and may damage the user's DNA...
Children With Sickle Cell Disease, Hypertension, And Anemia At Risk For Silent Strokes
11/30/2011
A team of researchers from the Johns Hopkins Children's Center, Vanderbilt University and elsewhere have demonstrated that high blood pressure and anemia together put children with sickle cell disease (SCD) at serious danger for symptomless or so-called "silent" strokes, although either condition alone also signaled high risk...
High Blood Sugar Levels In Older Women Linked To Colorectal Cancer
11/30/2011
Elevated blood sugar levels are associated with an increased risk of colorectal cancer, according to a study led by researchers at Albert Einstein College of Medicine of Yeshiva University. The findings, observed in nearly 5,000 postmenopausal women, appear in the November 29 online edition of the British Journal of Cancer...
Mammography Screening At 40 Supported By New Study
11/30/2011
Women in their 40s with no family history of breast cancer are just as likely to develop invasive breast cancer as are women with a family history of the disease, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). These findings indicate that women in this age group would benefit from annual screening mammography...
Spread Of Aggressive Uveal Melanoma Cells May Be Slowed By Seizure Drug
11/30/2011
A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers at Washington University School of Medicine in St. Louis. Their findings are available online in the journal Clinical Cancer Research...