Scientists Engineer Blood Stem Cells To Seek Out And Attack Melanoma
11/29/2011
Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers believe this approach could be useful in 40 percent of Caucasians with this malignancy...
What Wakes Dormant Tumor Cells
11/29/2011
Prostate tumor cells can be lulled to sleep by a factor released by bone cells, according to a study published online this week in the Journal of Experimental Medicine. Disease recurs in up to half of prostate cancer patients after treatment, often as a result of metastases that spread to distant organs...
Urinary Retention Due To Benign Enlarged Prostate Treated Differently In 15 Countries
11/29/2011
Men who experience a sudden inability to pass urine because of a non-cancerous enlarged prostate are hospitalised and treated differently depending on where they live, according to an international study published online by the urology journal BJUI...
Cell Molecule Identified As Central Player In The Formation Of New Blood Vessels
11/29/2011
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein Shc (pronounced SHIK), and new blood vessel formation, or angiogenesis, is seriously impaired without it...
UT MD Anderson Creates Institute To Accelerate Cancer Drug Development
11/29/2011
Academic and government leaders announced today the establishment of a major new research institute at The University of Texas MD Anderson Cancer Center that will blend the best attributes of academic and industrial research to identify and validate new cancer targets, convert such scientific knowledge into new cancer drugs, and advance these novel agents into innovative clinical trials...
An Unexpected Player In A Cancer Defense System
11/29/2011
Researchers of the Swedish medical university Karolinska Institutet and the University of Cologne, Germany, have identified a new protein involved in a defense mechanism against cancer. The VCP/p97 complex is best known for its role in protein destruction and is involved in a type of familial dementia and ALS...
Biopsy Of Recurrent Breast Cancer Can Alter Treatment
11/29/2011
A second, larger clinical research study led by breast cancer specialists at Princess Margaret Hospital (PMH) has again proven that comparing a new biopsy of progressing or recurring cancer with that of the original cancer can dictate a change in treatment. The results are published online today ahead of print in the Journal of Clinical Oncology. Principal investigator Dr...
Increased Risk Of Blood Clots On The Lung For Patients With Autoimmune Diseases
11/29/2011
In a nationwide study based on data from the in-patient register, researchers have studied the risk of a blood clot on the lung for patients with autoimmune diseases such as rheumatoid arthritis, inflammatory bowel disease and type 1 diabetes. The study showed that 31 of the 33 autoimmune diseases studied were associated with an increased risk of pulmonary embolism a blood clot on the lung...
Well-Done Red Meat May Increase Risk For Aggressive Prostate Cancer
11/28/2011
New research led by the University of California, San Francisco (UCSF), offers further evidence of a link between aggressive prostate cancer and meat consumption, and suggests it is driven largely by consumption of grilled or barbecued red meat, especially when it is well-done...
Study Identifies A Key Molecular Switch For Telomere Extension By Telomerase
11/28/2011
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ends by telomerase, an enzyme thought to play a key role in cancer and aging. Their findings are reported online in Nature Structural and Molecular Biology...