Poor Prognosis In Breast Cancer Linked To PI3K/mTOR Pathway Proteins
4/03/2012
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR Annual Meeting 2012...
Seeking Clues To Colon Cancer In Newly Identified Stem Cells
4/02/2012
Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer...
Angiogenesis, the growth of new blood vessels, is a complex process during which different signalling proteins interact with each other in a highly coordinated fashion. The growth factor VEGF and the Notch signalling pathway both play important roles in this process...
Mechanism Identified That Makes Breast Cancer Invasive
4/02/2012
A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer metastasis and identifies new therapeutic targets for a lethal form of invasive breast cancer that is notoriously resistant to treatment...
Preparations For Possible Study Of Cancer Risks Near US Nuclear Facilities
4/01/2012
A proposed study could help determine if there is a link between living near nuclear power plants or other nuclear facilities and having a higher risk of cancer, but challenges and limitations exist, says a new report from the National Research Council, the operating arm of the National Academy of Sciences and National Academy of Engineering...
HPV-Related Head & Neck Cancers Rising, Highest In Middle-Aged White Men
4/01/2012
Research led by Lauren Cole, a public health graduate student, and Dr. Edward Peters, Associate Professor of Public Health and Director of the Epidemiology Program at LSU Health Sciences Center New Orleans, reports that the incidence of head and neck cancer has risen at sites associated with Human Papilloma Virus (HPV) infection, with the greatest increase among middle-aged white men...
Low Recurrence And Cancer Death Rates Associated With Kidney Cancer Subtype
3/31/2012
Patients with papillary renal cell carcinoma, the second most common kidney cancer subtype, face a low risk of tumour recurrence and cancer-related death after surgery. Those are the key findings of a multi-centre study of nearly 600 patients published in the April issue of the urology journal BJUI...
New Technology Reveals Breast Cancer Risk Gene
3/31/2012
An international team of researchers led by the University of Melbourne has used new technology to fast track the discovery of a breast cancer risk gene which could assist in the discovery of other cancer genes...
Roche's Trastuzumab Emtansine Has Positive Results Against Metastatic Breast Cancer
3/30/2012
Roche released an announcement today in regards to its phase three trial called EMILIA. The program compared performance of its new drug Trastuzumab Emtansine against standard treatments for HER2-positive Metastatic Breast Cancer that use lapatinib plus Xeloda® (capecitabine). Patients were enrolled in the study having previously received Herceptin® and ataxane (chemotherapy)...
Intralesional PV-10 Treatment Shows Promise For Some Melanoma Patients
3/30/2012
At the 2012 Society of Surgical Oncology Annual Meeting, Provectus Pharmaceuticals Inc. presented non-clinical information on PV-10s immunologic mechanism, which confirms that the drug's chemoablation of melanoma lesions results in a systemic response and initiates systemic anti-tumor immunity...