Huge Cancer Knowledge Resource Made Public
3/30/2012
Bringing the goal of personalized medicine a step closer, scientists who design anti-cancer treatments and clinical trials now have access to a huge cancer knowledge resource, thanks to a collaboration between industry and academia...
New Cancer Rates In Adults Fell And In Children Rose, USA
3/30/2012
New cancer rates among men fell 0.6% annually from 1994 to 2008, among women they dropped 0.5% yearly from 1998 to 2006, and among children rose from 1992 to 2008, according to the Annual Report to the Nation on the Status of Cancer, which was published in the journal Cancer. From 2004 to 2008, average cancer death rates for both sexes dropped by 1.6% annually...
First Volume Of The Cancer Cell Line Encyclopedia Made Public
3/30/2012
The goal of cancer treatment is to match the right drug to the right target in the right patient. But before such "personalized" drugs can be developed, more knowledge is needed about specific genomic alterations in cancers and their sensitivity to potential therapeutic agents...
Public Health Researchers Outline Obstacles Standing In The Way Of Cancer Prevention
3/30/2012
More than half of all cancer is preventable, and society has the knowledge to act on this information today, according to Washington University public health researchers at the Siteman Cancer Center in St. Louis...
Potential New Way Of Preserving Fertility For Boys Undergoing Cancer Treatment
3/30/2012
Treatments for childhood cancers are increasingly successful with cure rates approaching 80%, but success often comes with a downside for the surviving men: the cancer treatments they received as boys can leave them sterile as adults...
BMI Not Found To Play A Role In Surgical Complications Or In Survival
3/30/2012
Researchers at Moffitt Cancer Center in Tampa, Fla., have found - contrary to previous studies linking inferior outcomes in patients with gastrointestinal malignancies to higher body mass index (BMI) - that in their study of BMI and negative outcomes, there was no such link. They concluded that BMI was not associated with either surgical complications or esophageal cancer patient survival...
Diagnostic Hope For Children's Cancer Following Discovery Of Genetic Abnormality
3/30/2012
A chromosomal abnormality in children with a deadly form of brain cancer is linked with a poorer chance of survival, clinician scientists at The University of Nottingham have discovered...
Recurring Breast Cancer Diagnosed A Year Earlier With New, More Sensitive Blood Test
3/30/2012
A new blood test is twice as sensitive and can detect breast cancer recurrence a full year earlier than current blood tests, according to a scientist who reported at the 243rd National Meeting & Exposition of the American Chemical Society (ACS)...
In Breast Cancer, Protein 'Jailbreak' Helps Cancer Cells Live
3/30/2012
If the fight against breast cancer were a criminal investigation, then the proteins survivin, HDAC6, CBP, and CRM1 would be among the shadier figures. In that vein, a study to be published in the March 30 Journal of Biological Chemistry is the police report that reveals a key moment for keeping cancer cells alive: survivin's jailbreak from the nucleus, aided and abetted by the other proteins...
Personalized Cancer Therapy - Profiling Genetic Changes
3/29/2012
Profiling genetic alterations in cancer with drug sensitivity is a way to develop a tailored approach to treating patients with cancer, researchers from Europe and the USA reported in the journal Nature. In what they describe as the "largest study of its kind", hundreds of associations between cancer gene mutations and anticancer medication sensitivity or resistance have been uncovered...