Should Parents Disclose A Genetic Predisposition To Breast Cancer To Their Children?
4/03/2012
When a mother undergoes genetic testing to determine whether she carries a gene for hereditary breast cancer, the parents must then decide whether and how to share this risk information with their children...
Galeterone Shown To Be Safe, Effective Against Prostate Cancer In Phase I Trial
4/03/2012
Patients with castration-resistant prostate cancer had limited side effects and in many cases a drop in prostate-specific antigen expression with galeterone (TOK-001), a small-molecule oral drug, according to phase I data presented at the AACR Annual Meeting 2012, being held March 31 - April 4...
Prostate Cancer Recurrence Predicted By Oxygen In Tumors
4/03/2012
Low oxygen levels in tumors can be used to predict cancer recurrence in men with intermediate-risk prostate cancer even before they receive radiation therapy...
Detection Of Lung Cancers Via CT Screening As Successful As Traditional Methods
4/03/2012
A new study led by researchers at Mount Sinai School of Medicine indicates that CT scans are more effective than traditional lung cancer detection methods at identifying aggressive lung cancers in their most treatable stages...
Stem Cells From Intestinal Crypt Lead Researchers To Cancer Discovery
4/03/2012
Tales from the crypt are supposed to be scary, but new research from Vanderbilt University, the HudsonAlpha Institute for Biotechnology and colleagues shows that crypts can be places of renewal too: intestinal crypts, that is. Intestinal crypts are small areas of the intestine where new cells are formed to continuously renew the digestive tract...
Laying The Foundation For Personalized Cancer Treatment Using DNA Sequencing
4/03/2012
Scientists at Washington University School of Medicine in St. Louis are using powerful DNA sequencing technology not only to identify mutations at the root of a patient's tumor - considered key to personalizing cancer treatment - but to map the genetic evolution of disease and monitor response to treatment...
Identification Of Biomarker In Relation To Drug Response In Refractory Urothelial Cancer
4/03/2012
The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. The results also revealed that increases in interleukin-8 levels early after treatment with pazopanib may predict a lack of tumor response to the therapy...
A pair of targeted therapies shrank tumors in some patients with treatment-resistant Ewing's sarcoma or desmoplastic small-round-cell tumors, according to research led by investigators from The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2012...
Diabetes Drug Metformin May Help To Prevent Primary Liver Cancer
4/03/2012
Metformin, a drug widely used to treat Type II diabetes, may help to prevent primary liver cancer, researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center report in the April 2012 issue of Cancer Prevention Research...
Metastatic Breast Cancer And Arthritis Link
4/03/2012
New research shows it may be no accident when doctors observe how patients suffering from both breast cancer and arthritis seem to have more aggressive cancer. However, the new-found interaction between the two diseases may also suggest a possible treatment...