Key Protein Players Identified In Hard-To-Treat Breast Cancers
4/04/2012
At the time of diagnosis, the majority of breast cancers are categorized as estrogen-receptor positive, or hormone sensitive, which means their cancerous cells may need estrogen to grow. Patients with this type of cancer often respond favorably to treatments called aromatase inhibitors, like tamoxifen, which cause cell death by preventing estrogen from reaching the cancerous cells...
Treating Endocrine Resistant Breast Cancer Cells: 2 Specific Agents Worse Than 1
4/04/2012
A new class of agents known as c-Src inhibitors is being tested in a number of different ways to treat breast cancer, but researchers at Georgetown Lombardi Comprehensive Cancer Center caution that they should not be used in combination with estrogen to treat endocrine resistant breast cancer...
News From The Annals Of Internal Medicine: April 3, 2012
4/04/2012
1. Mammography Screening Leads to Overdiagnosis of Breast Cancer Women undergo mammography screening to detect cancer in its early stages. Theoretically, early detection saves lives. However, newer research is questioning whether finding cancer early is better. Researchers in Norway sought to determine the percentage of overdiagnosis of breast cancer attributable to mammography screening...
Metal-On-Metal Hip Replacement No Extra Cancer Risk At Seven Years
4/03/2012
According to a study in bmj.com, the risk of developing cancer within the first seven years after receiving a metal-on-metal hip replacement is no higher than in the general population, although further long-term studies are required...
Routine Mammograms: 10 Patients Wrongly Diagnosed For Every 1 Saved
4/03/2012
The "should we shouldn't we" debate continues in regards to routine breast cancer screening, with new research from Harvard School of Public Health (HSPH), indicating that between 15% and 25% of cases are overdiagnosed. Routine mammograms have become the norm since the late 1980s, and have been thought to be the frontline in the fight against breast cancer...
Head And Neck Cancer Chemotherapy Efficacy Boosted By Human Virus
4/03/2012
Preliminary data from a trial published in Clinical Cancer Research shows that a harmless human virus that occurs naturally could potentially boost the effects of two standard chemotherapy drugs in some cancer patients. Oncolytics Biotech Inc. developed a new drug, RT3D that will be marketed under the trade name of Reolysin. The drug is based on a virus, i.e...
Higher Cost But Fewer Deaths, Complications With Robotic Bladder Cancer Surgery
4/03/2012
With technological advancements opening the door to less invasive medical procedures, robotic-assisted surgery is becoming increasingly popular, despite being more expensive than traditional surgery. Robotic-assisted surgical removal of the bladder due to cancer is a new approach to the traditional "open" - or more invasive - operation called a radical cystectomy...
In Vivo Inflammation And Metastasis Visualized In Genetically Modified Mice
4/03/2012
One of the major routes of tumor cell dissemination to form metastasis at distant organs in the body is the lymphatic system...
Alarming Rise In Skin Cancer Rates
4/03/2012
Science and better living habits are starting to conquer some types of cancers, but skin cancer seems to be becoming rather prevalent. Mayo Clinic researchers published their study in the April issue of Mayo Clinic Proceedings, showing that the incidence of melanoma has escalated dramatically, especially amongst young women. Lead investigator Jerry Brewer, M.D...
Prediction Of Increased Survival In Sarcoma Patients Using Early PET Response To Neoadjuvant Chemo
4/03/2012
An early Positron Emission Tomography (PET) response after the initial cycle of neoadjuvant chemotherapy can be used to predict increased survival in patients with soft tissue sarcomas, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center...