Caffeine, Exercise May Cut Skin Cancer Risk
4/04/2012

A new study of mice reported at a meeting in Chicago this week, suggests caffeine and exercise may cut the risk of developing skin cancers caused by exposure to the sun...

Identification Of Strong Oral Carcinogen In Smokeless Tobacco
4/04/2012

The chemical (S)-N'-nitrosonornicotine, or (S)-NNN, which is present in smokeless tobacco products, is a strong oral carcinogen, according to results presented at the AACR Annual Meeting 2012, being held March 31 - April 4...

Indoor Tanning Bed Use, Childhood Sunburns May Be Responsible For Dramatic Rise In Skin Cancer In Young Adults
4/04/2012

Even as the rates of some cancers are falling, Mayo Clinic is seeing an alarming trend: the dramatic rise of skin cancer, especially among people under 40. According to a study by Mayo Clinic researchers published in the April issue of Mayo Clinic Proceedings, the incidence of melanoma has escalated, and young women are the hardest hit...

Second Mutation In BRAF-Mutated Melanoma Doesn't Contribute To Resistance
4/04/2012

A second mutation found in the tumors of patients with BRAF-mutated metastatic melanoma does not contribute to resistance to BRAF inhibitor drugs, a finding that runs counter to what scientists expected to be true...

News From The Journal Of Clinical Investigation: April 2, 2012
4/04/2012

METABOLISM Linking obesity and high cholesterol Obese patients are at increased risk for cardiovascular disease and a hardening of blood vessel walls called atherosclerosis. One factor that drives atherosclerosis development in obesity is abnormal blood cholesterol levels...

Metformin Helps Some Cancer Patients
4/04/2012

A popular diabetes drug, metformin, appears to help patients with several types of cancer, including cancer of the prostate, liver and pancreas, researchers are revealing or are about to reveal at the American Association For Cancer Research Meeting, 2012, Chicago, USA...

Antitumor Effect Shown By Cancer Stem Cell Vaccine In Development
4/04/2012

Scientists may have discovered a new paradigm for immunotherapy against cancer by priming antibodies and T cells with cancer stem cells, according to a study published in Cancer Research, a journal of the American Association for Cancer Research...

New Clues To The Development Of Blood And Other Cancers
4/04/2012

Scientists at Fox Chase Cancer Center have uncovered more details about how defects in components of the machinery that makes new proteins can lead to blood and other cancers. The findings, which were presented at the AACR Annual Meeting 2012, may one day lead to new targeted therapies that address those problems...

Association Between Protein Aurora-A And Survival In Head And Neck Cancer
4/04/2012

Researchers at Fox Chase Cancer Center in Philadelphia have found that a protein associated with other cancers appears to also be important in head and neck cancer, and may consequently serve as a good target for new treatments. The findings were reported at the AACR Annual Meeting...

Link Between New Signaling Pathway And Breast Cancer Metastasis
4/04/2012

Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave the primary tumor is in the lymph nodes...