CT Screening Reduces Lung Cancer Deaths
5/07/2013
CT (computed tomography) screening can reduce lung cancer deaths among high-risk individuals, according to results from the National Lung Cancer Study...
Weekend Visits To ER May Lead To Greater Risk Of Mortality For Some Prostate Cancer Patients
5/07/2013
Patients with prostate cancer that has metastasized, or spread, to other parts of the body face a significantly higher risk of dying when visiting a hospital emergency department on the weekend instead of on a weekday, according to researchers at Henry Ford Hospital in Detroit...
Novel Therapeutic Approach To Treating Inflammation In Cardiovascular Disease
5/07/2013
Peptide receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogs, an established treatment for cancer patients, could offer a novel therapeutic approach to decrease levels of inflammation in the atherosclerotic plaques of patients with cardiovascular disease (CVD), reported an abstract¹ study at the International Conference on Nuclear Cardiology and Cardiac ...
Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer...
Tanning Bed Risks - FDA Aims To Increase Consumer Awareness
5/07/2013
The U.S. Food and Drug Administration (FDA) wants to reclassify sunlamp products so that their labeling includes a recommendation against young people using them. For the moment, the FDA move is just a proposed order that it aims to eventually finalize...
The Energy Landscape Of Ion Channels Revealed By Computer Simulations
5/07/2013
Ion channels are important drug targets. A young team of researchers led by pharmacologist Anna Stary-Weinzinger from the Department of Pharmacology and Toxicology, University of Vienna investigated the opening and closing mechanisms of these channels: for the first time the full energy landscape of such a large protein ( 400 amino acids) could be calculated in atomic detail...
Researchers Discover New Target For Personalized Cancer Therapy
5/07/2013
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a novel method to disrupt this growth signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers...
DNA Housekeeping Proteins May Also Prevent Cancer
5/06/2013
Scientists once thought BAF proteins confined their activity to cellular housekeeping. But then they discovered these complexes do more than help package and maintain DNA in cells: it seems they also suppress tumor development in many types of tissue...
Using DCIS Score To Quantify Risk Of IBE For Breast Cancer Patients
5/06/2013
The ductal carcinoma in situ (DCIS) Score quantifies the risk of ipsilateral breast event (IBE) and invasive IBE risk, complements both traditional clinical and pathologic factors, and helps provide a new clinical tool to improve the process of selecting individualized treatment for women with DCIS who meet the criteria, according to a study published in the Journal of the Nati...
Blocking A Single Gene Renders Tumors Less Aggressive
5/06/2013
Researchers at Johns Hopkins have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The researchers hope that this so-called "master regulator" gene may be the key to developing a new treatment for tumors resistant to current drugs...