Everolimus Can Overcome Trastuzumab Resistance In HER-2 Positive Early Breast Cancer
5/06/2013
A study that aimed to understand how the cancer drug everolimus helps overcome the resistance breast cancers can develop to trastuzumab has left researchers contemplating a puzzle. The study showed a statistically non-significant benefit in clinical response rates for some patients with early breast cancer when everolimus was added to treatment with trastuzumab...
STD's Not Cancer Prevention Should Be The Focus For Promoting HPV Vaccine
5/06/2013
The HPV vaccine can prevent both cervical cancer and a nasty sexually transmitted disease in women. But emphasizing the STD prevention will persuade more young women to get the vaccine, a new study suggests. These results go against the conventional wisdom that scaring women about the possibility of cancer is the best way to get them vaccinated...
Cervical Cancer Detection In Kenya Via Self-Collection Of Samples For HPV Testing
5/06/2013
In Kenya, women face a cervical cancer mortality rate that is approximately 10 times as high as in the United States. A study by researchers at the University of North Carolina at Chapel Hill suggests that training women to self-collect genital samples to test for human papillomavirus (HPV), the causative agent of cervical cancer, can increase the coverage rates of cervical cancer screening...
Discovery Improves Understanding Of The Biology That Underlies Breast And Ovarian Cancers
5/06/2013
A major international study involving a Simon Fraser University scientist has found that sequence differences in a gene crucial to the maintenance of our chromosomes' integrity predispose us to certain cancers...
A test that measures the expression levels of 58 genes in oestrogen receptor-positive breast cancers can effectively differentiate between patients who are at higher and lower risk for having their cancer recur elsewhere in the body more than five years after diagnosis, researchers report...
No Barrier To Predictive Testing Found In Breast Cancer Heterogeneity
5/06/2013
Breast cancers contain many different cell types with different patterns of gene expression, but a new study provides reassurance that this variability should not be a barrier to using gene expression tests to help tailor cancer treatments to individual patients. The findings were reported at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium...
Potential New Targeted Therapies For Breast Cancer
5/06/2013
A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalised therapy for breast cancer a step closer, researchers said at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium...
The Magnitude Of Variation In Gene Expression Measurements Within Breast Cancers Revealed By Study
5/06/2013
An important new study has revealed the clearest picture yet of precisely how much measurement variation influences gene expression profiles of breast cancer. The results show, for the first time, which gene expression measurements may benefit from pooling of biopsies from a single tumour, researchers said at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium...
In Estrogen Receptor POS Breast Cancer, Genetic And Clinical Factors Best To Predict Late Recurrence
5/06/2013
A new analysis has provided a comprehensive comparison of scores designed to predict which women with oestrogen-receptor positive breast cancer are at high risk of recurrence beyond five years after diagnosis, and may benefit from prolonged endocrine treatment...
Solving the structure of a critical human molecule involved in cancer, scientists at The Scripps Research Institute (TSRI) have found what they call a good example of structural conservation - dissimilar genes that keep very similar shapes...