Wip1 Could Be New Target For Treatment Of Colorectal, Breast And Ovarian Cancers
5/08/2013
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new target for the treatment of certain cancers. Like a battlefield surgeon who has to decide which casualties can be saved, p53 performs triage on cells with injured DNA...
Sleep Problems Double Men's Risk Of Prostate Cancer
5/08/2013
Sleep problems, such as difficulty falling asleep and staying asleep, double the risk of prostate cancer in men, according to new research. The study was conducted by a team at the University of Iceland in Reykjavik and was published in the journal Cancer Epidemiology, Biomarkers & Prevention. Lara G. Sigurdardóttir, M.D...
Low-Volume Institutions Experience Inferior Outcomes In Prostate Cancer Surgery
5/08/2013
The volume of cases performed at an institution each year has a direct effect on the outcome of surgical procedures, and should always be considered when looking at the benefits of a technique, according to a team of researchers at Henry Ford Hospital in Detroit. Those conclusions were presented at the annual meeting of the American Urological Association in San Diego...
Detecting Recurrent Lung Cancer At An Earlier Stage Using Minimal Dose CT
5/08/2013
Lung cancer is associated with very high mortality, in part because it is hard to detect at early stages, but also because it can recur frequently after surgical removal. The question arises as to what is the best way to follow lung cancer patients after surgery in order to spot problems early enough, before symptoms become obvious, so that patients may still be eligible for new interventions...
HPV Vaccine - Young Women Motivated More By STD Than Cancer Protection
5/08/2013
Young women are more likely to take the HPV vaccine if they are told it protects from a nasty sexually transmitted disease, even though it also protects from potentially deadly cervical cancer, researchers from The Ohio State University and Texas Tech University discovered...
Study Findings Could Lead To Treatments In Cancer, Neurological Diseases
5/08/2013
Kansas State University scientists helped discover new details about an intricate process in cells. Their finding may advance treatments for cancer and neurological diseases. Kansas State University researchers Jeroen Roelofs, assistant professor, and Chingakham Ranjit Singh, research assistant professor -- both in the Division of Biology -- led part of the study...
Study Shows Protein Complex May Play Role In Preventing Many Forms Of Cancer
5/08/2013
Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues...
Researchers Discover How Breast Cancer Spreads
5/08/2013
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. It has long been known that women with denser breasts are at higher risk for breast cancer...
Anemia increases operative mortality and morbidity in non-cardiac and cardiac surgical procedures. Anemic surgical patients may require more blood transfusions, raising the risk of transfusion-related complications and increasing costs. For those reasons, optimizing patient readiness by correcting anemia prior to surgery is an important clinical goal...
Nerve Protecting Agents May Help Prevent Chemotherapy-Induced Anemia
5/08/2013
Cancer chemotherapy can cause peripheral neuropathy - nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that chemo also induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation...