Gene Transfer May Play Role In Cancer, Other Diseases Linked With DNA Damage
6/27/2013
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, scientists have found. The researchers, affiliated with the University of Maryland School of Medicine's Institute for Genome Sciences, analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas...
After Lumpectomy For Breast Cancer, Rural Women Less Likely To Get Radiation Therapy
6/27/2013
Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found. The difference is one of several rural disparities in breast cancer diagnosis and treatment the researchers discovered...
The only therapy available for a disease with a clear unmet medical need will not be made available to UK patients Novartis today expressed disappointment at the National Institute for Health and Clinical Excellence's (NICE) decision to publish final guidance not recommending ruxolitinib (INC424, Jakavi™) for the treatment of disease-related splenomegaly (enlarged spleen...
Xtandi™ (Enzalutamide) Authorised In The European Union (EU) For Advanced Prostate Cancer
6/26/2013
Enzalutamide authorised in European Union (EU) for the treatment of adult men with metastatic castrationresistant prostate cancer whose disease has progressed on or after docetaxel therapy[1] Astellas Pharma Europe Ltd., the European Headquarters of Tokyobased Astellas Pharma Inc. (TSE:4503), and Medivation, Inc...
Nanoparticles that deliver short strands of RNA offer a way to treat cancer and other diseases by shutting off malfunctioning genes. Although this approach has shown some promise, scientists are still not sure exactly what happens to the nanoparticles once they get inside their target cells...
Genomic Alterations Tied To Kidney Tumor Aggressiveness Identified
6/26/2013
Investigators in The Cancer Genome Atlas (TCGA) Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear cell renal cell carcinoma (ccRCC)...
Hunger For Amino Acids Makes Brain Cancer More Aggressive
6/26/2013
To fuel phases of fast and aggressive growth, tumors need higher-than-normal amounts of energy and the molecular building blocks needed to build new cellular components. Cancer cells therefore consume a lot of sugar (glucose A number of tumors are also able to catabolize the amino acid glutamine, an important building block of proteins...
Breast Cancer Stem Cells Destroyed By Targeted Viral Therapy In Preclinical Experiments
6/26/2013
A promising new treatment for breast cancer being developed at Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine (VIMM) has been shown in cell culture and in animal models to selectively kill cancer stem cells at the original tumor site and in distant metastases with no toxic effects on healthy cells, including normal stem cells...
Advanced Prostate Cancer Treatment Usage Rising Fast In Low Risk Patients
6/26/2013
More men with low-risk prostate are undergoing advanced treatment, including robotic prostatectomies and intensity-modulated radiotherapy, even though their risk of non-cancer mortality is much higher, researchers from University of Michigan, Ann Arbor, reported in JAMA (June 26th 2013 issue)...
High-End Treatment For Low Risk Prostate Cancer Rising
6/26/2013
More men with low-risk prostate are undergoing robotic prostatectomies and intensity-modulated radiotherapy, even though their risk of non-cancer mortality is much higher, researchers from University of Michigan, Ann Arbor, reported in JAMA (June 26th 2013 issue). The authors added that these low-risk prostate cancer patients will likely not benefit from advanced treatment technologies...