Immunohistochemistry Could Be A Reliable And Cost-Effective Diagnostic Approach In Lung Cancer
6/28/2013
ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors...
Cancer-Promoting Mechanisms Of Overlooked Components In Secondhand Smoke
6/28/2013
Tobacco smoke, diesel exhaust and oil combustion carry polycyclic aromatic hydrocarbons - PAHs that are known to cause cancer. But of these PAHs, the obviously dangerous high-molecular-weight PAHs like benzo[a]pyrene (BaP) have received the vast majority of research attention...
Prototype Device Aims To Avert Repeated Breast Cancer Surgeries
6/28/2013
When a breast tumor is detected, many women opt to have a lumpectomy, which is surgery designed to remove the diseased tissue while preserving the breast. But during this procedure, doctors cannot learn right away whether all of the cancerous tissue has been removed, with no microscopic signs that cancer cells were left behind...
FDA Approves Hemophilia B Drug "Rixubis"
6/28/2013
The FDA has just approved the drug Rixubis [Coagulation Factor IX (Recombinant)] for people over the age of 16 suffering from hemophilia B. Hemophilia B is an inherited chronic blood disorder where the blood does not clot properly, it is caused by mutations in the Factor IX gene. The symptoms of hemophilia are characterized by serious bleeding (particularly in the joints) and easy bruising...
Small Proteins Unique To Melanoma Cells Rapidly Identified By New Screening Approach
6/27/2013
Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells. These fragments can be used as targets for tumor-infiltrating lymphocytes that have been shown to reduce cancerous lesions...
Project To Improve Molecular Diagnosis Of Lynch Syndrome
6/27/2013
The Fundacion Mutua Madrilena, in its 10th Call for Aids to Research, has selected a project to improve the diagnosis of Lynch syndrome led by researcher Marta Pineda, from the Hereditary Cancer research group of the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO). The aid is provided with 33,000 euros and has a duration of two years...
UK Lags Behind EU Counterparts In Uptake Of Oncology Biomarker Testing
6/27/2013
Research reveals that the uptake of diagnostic testing amongst cancer patients in the UK trails behind that of other Western European markets...
Nitric Oxide Repletion Of Stored Blood Improves Post-Procedural Outcomes
6/27/2013
Researchers from Case Western Reserve University School of Medicine have developed an unprecedented approach to restore nitric oxide (NO) to donated blood, a breakthrough that could dramatically reduce harmful effects from transfusions...
Aspirin's Preventive Colon Cancer Effect Depends On Genes
6/27/2013
Taking a daily dose of aspirin helps lower the risk of colon cancer. However, a new study has found that the reduced risk of colorectal cancer is affected by a mutation of a gene called BRAF. Colon cancer is a leading cause of cancer-related death worldwide. In 2008, there were 1.23 million new clinically diagnosed cases of colorectal cancer; over 608,000 people died from the disease that year...
Heart Failure Survivors At Increased Cancer Risk
6/27/2013
Heart failure patients are surviving more often with the heart condition but they are increasingly more likely to be diagnosed with cancer, a trend that could be attributed to increased surveillance, side effects of treatments, or other causes, according to a study published online in the Journal of the American College of Cardiology...