Progress, challenges in childhood cancer outlined in report
2/04/2014

A new report from the American Cancer Society outlines progress made and - more importantly - challenges that remain in fighting childhood cancer.

Protocol developed to harvest mouse cell lines for melanoma research
2/04/2014

Dartmouth researchers have developed a protocol that permits cells harvested from melanoma tumors in mice to grow readily in cell culture. Their findings were published in an article, Multiple murine BRafV600E melanoma cell lines with sensitivity to PLX4032, in the journal Pigment Cell & Melanoma Research.

Success reported in targeted therapy for common form of lung cancer
2/04/2014

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

Protein serves as a natural boost for immune system fight against tumors
2/04/2014

Substances called adjuvants that enhance the body's immune response are critical to getting the most out of vaccines. These boosters stimulate the regular production of antibodies -- caused by foreign substances in the body -- toxins, bacteria, foreign blood cells, and the cells of transplanted organs.

Genetically diverse cancer cells key to brain tumor resistance
2/04/2014

For a cancer cell, it pays to have a group of eccentric friends. Like X-Men characters, a group of cancer cells with diverse physical traits is safer, because it takes different strategies to kill each member.The more diverse the group, the better the chances are for individual cells to survive and join forces as a cohesive tumor.

Marker may predict response to ipilimumab in advanced melanoma
2/04/2014

Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.

Success reported in targeted therapy for common form of lung cancer
2/04/2014

The most common genetic subtype of lung cancer, which has long defied treatment with targeted therapies, has had its growth halted by a combination of two already-in-use drugs in laboratory and animal studies, setting the stage for clinical trials of the drugs in patients, researchers at Dana-Farber Cancer Institute and other scientists report in a new study.

Simple, at-home test will detect most colorectal cancers
2/03/2014

Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79 percent of colorectal cancers, according to a new evidence review published in the Annals of Internal Medicine.

Simple, at-home test will detect most colorectal cancers
2/03/2014

Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79 percent of colorectal cancers, according to a new evidence review published in the Annals of Internal Medicine.

HPV vaccine 'does not lead to risky sexual behavior in teens'
2/03/2014

Some parents might worry that the human papillomavirus vaccine could lead to more sex or more unsafe sex in teenagers and young people. However, a new study conducted by the Cincinnati Children's Hospital Medical Center in Ohio and published in the Pediatrics journal finds that these concerns are unwarranted.