The Goldilocks effect in cancer
4/07/2014
Too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including proliferation, researchers at the University of California, San Diego School of Medicine have found.The findings are published in the current online issue of Molecular Cell.
New drug delivery method fights cancer with lasers and nanoballoons that pop
4/07/2014
Chemotherapeutic drugs excel at fighting cancer, but they're not so efficient at getting where they need to go. They often interact with blood, bone marrow and other healthy bodily systems. This dilutes the drugs and causes unwanted side effects.
Diffeomorphometry and geodesic positioning systems for human anatomy
4/06/2014
New algorithmic technologies demonstrated for the parametric representation of human shape and form by a team of researchers from the Center for Imaging Science at the Johns Hopkins University and the CMLA of the Ecole Normale Suprieure Cachan.
Novel biomarker identified for head and neck cancer, non-small cell lung cancer
4/05/2014
A new biomarker linked to better outcomes for patients with head and neck cancers and non-small cell lung cancer has been identified by a team led by a scientist from the Florida campus of The Scripps Research Institute (TSRI). The work could help scientists develop new diagnostics and therapies and help physicians determine the best long-term treatments for patients with these cancers.
For treating tumors, radiation can be safely and effectively stored in nontoxic molecule
4/05/2014
Microscopic "bubbles" developed at Kansas State University are safe and effective storage lockers for harmful isotopes that emit ionizing radiation for treating tumors.The findings can benefit patient health and advance radiation therapy used to treat cancer and other diseases, said John M.
Scientists identify protein that spurs spread of colon cancer
4/04/2014
PLAC8, a protein that until now has been poorly understood, appears to play a key role in the spread - or metastasis - of colorectal or colon cancer.Previous research has already found that PLAC8 is linked to colon cancer. Now, in a new study published in the Journal of Clinical Investigation, researchers from Washington University School of Medicine in St.
Lack of insurance coverage a barrier to lung cancer screening
4/04/2014
The majority of current and former smokers would welcome screenings for lung cancer if their insurance covered the spiral computed tomography (CT) scans, according to research from Roswell Park Cancer Institute (RPCI) and the Medical University of South Carolina and published online ahead of print in the journal Lung Cancer.
Team identifies novel biomarker for head and neck cancer and non-small cell lung cancer
4/04/2014
A team led by a scientist from the Florida campus of The Scripps Research Institute (TSRI) has identified a new biomarker linked to better outcomes of patients with head and neck cancers and non-small cell lung cancer. The work could help scientists develop new diagnostics and therapies and help physicians determine the best long-term treatments for patients with these cancers.
Melanoma-dependent immune dysfunction predicted by NOS1 expression
4/04/2014
Individuals with cancer often exhibit dysfunctional immune signaling in response to interferon (IFN) stimulation. Furthermore, recent evidence indicates that pSTAT-1 levels, which are indicative of IFN responsiveness, in circulating immune cells are predictive of clinical outcome in melanoma patients.
How zinc regulates a key enzyme involved in cell death
4/04/2014
The study is featured on the cover of the April issue of the journal Angewandte Chemie's International Edition.The molecular details of how zinc, an essential trace element of human metabolism, interacts with the enzyme caspase-3, which is central to apoptosis or cell death, have been elucidated in a new study led by researchers at Virginia Commonwealth University.