Alcohol Metabolism Causes DNA Damage And Triggers A Breast Cancer-Related DNA Damage Response
9/18/2011
Alcohol is known to be carcinogenic to humans in the upper aerodigestive tract, liver, colorectum, and the female breast. Evidence suggests that acetaldehyde, the primary metabolite of alcohol, plays a major role in alcohol-related esophageal cancer...
Indications Of An Additional Benefit From Prasugrel For Some Patients, But Also Of Greater Harm
9/18/2011
Compared with clopidogrel, non-fatal heart attacks occur less often in certain patients, but major bleeding events are more common In order to better prevent blood clots, the drugs clopidogrel or prasugrel can be prescribed to patients with acute ischaemia of the heart muscle, in addition to acetylsalicylic acid (ASA)...
ApoPharma Inc. announced that the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted 10 - 2 to recommend that the FDA grant accelerated approval of Ferriprox® (deferiprone), an oral iron chelator, for the treatment of patients with transfusional iron overload when current chelation therapy is inadequate...
Stopping Brain Cancer Cells Feeding On Cholesterol Could Be A New Treatment
9/17/2011
Brain tumor cells feed on cholesterol, and blocking their access to it may offer a new way of treating glioblastoma, the most deadly form of brain cancer, and perhaps other cancers too, say US researchers in a new study published online this week in the journal Cancer Discovery...
Genetics May Explain Why Calcium Increases Risk For Prostate Cancer
9/17/2011
A study by epidemiologists at Wake Forest Baptist Medical Center and colleagues suggests that a high intake of calcium causes prostate cancer among African-American men who are genetically good absorbers of the mineral. "High dietary intake of calcium has long been linked to prostate cancer but the explanation for this observation has been elusive," said Gary G. Schwartz, Ph.D...
Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company"), a leading RNA interference (RNAi) therapeutics company, announces the issuance of patent 4810095 entitled "Use of Protein Kinase N beta" by the Japanese Patent Office...
Chemotherapy-Induced Neuropathic Pain; The Pain Of Surviving Cancer
9/17/2011
Thanks to greater awareness, earlier detection and improving therapeutic agents, people with cancer are living longer than ever before. One of the consequences of living longer is the symptom burden of cancer survivorship, which may have a substantial impact on quality of life for many survivors. One such burden is the pain syndromes resulting from cancer treatments...
Revealing The Inner Workings Of The Virus Responsible For A Rare Skin Cancer
9/16/2011
Scientists at the University of Pittsburgh Cancer Institute have begun to uncover how the virus that causes most Merkel cell carcinoma - a rare and aggressive skin cancer - operates, meaning that a rational chemotherapeutic target for this cancer could be developed in the near future. Patrick Moore, M.D., M.P.H...
Stopping Brain Cancer Cells Feeding On Cholesterol Could Be A New Treatment
9/16/2011
Brain tumor cells feed on cholesterol, and blocking their access to it may offer a new way of treating glioblastoma, the most deadly form of brain cancer, and perhaps other cancers too, say US researchers in a new study published online this week in the journal Cancer Discovery...
Writing Positively About Their Experience Benefits Men With Testicular Cancer
9/16/2011
Men who channeled positive thoughts into a five-week writing assignment about their testicular cancer showed signs of improved mental health afterward, in contrast to men who wrote negatively or neutrally about their condition, according to results of a Baylor University pilot study...