Newest Cancer Therapies Multi-Task To Eliminate Tumors
9/19/2011
Some of the newest therapies in the war on cancer remove the brakes cancer puts on the immune system, Georgia Health Sciences University researchers report. These immunotherapies, such as CTLA4, strengthen the immune system's attack on cancer by keeping apart two proteins that prevent key immune cells called T cells from activating...
Utilizing A Virus As A Potential Future Cancer Medicine
9/19/2011
In a new project, researchers from LIFE - the Faculty of Life Sciences at the University of Copenhagen - document that the vesicular stomatitis virus (VSV) plays a previously unknown dual role in the prevention of a number of cancers...
Potential Molecular Target To Prevent Growth Of Cancer Cells Identified By Researchers
9/19/2011
Researchers have shown for the first time that the protein fortilin promotes growth of cancer cells by binding to and rendering inert protein p53, a known tumor suppressor...
Quantifying Biochemical Cell Signals For First Time
9/19/2011
Just as cell phones and computers transmit data through electronic networks, the cells of your body send and receive chemical messages through molecular pathways. The term "cell signaling" was coined more than 30 years ago to describe this process...
Protein Critical To Breast Cancer Cell Proliferation, Migration Discovered
9/19/2011
Researchers have found that a protein linked to cell division and migration and tied to increased cell proliferation in ovarian tumors is also present at high levels in breast cancer specimens and cell lines. The protein, dubbed "UNC-45A," was also determined to be more active in breast cancer cells than in normal breast cells...
Researchers Find Possible Key To Preventing Chemotherapy Resistance In Ovarian Cancer
9/18/2011
For patients with ovarian cancer and their physicians, resistance to chemotherapy is a serious concern. However, researchers at Moffitt Cancer Center have identified a molecular pathway that may play a key role in the evolution of chemotherapy resistance...
Findings In Hibernating Arctic Ground Squirrels Have Implications For Human Health
9/18/2011
When Arctic ground squirrels are getting ready to hibernate they don't just get fat - they pack on muscle at a rate that would make a bodybuilder jealous. And they do it without suffering the harmful effects that high levels of testosterone and other anabolic steroids usually cause...
Researchers Find Possible Key To Preventing Chemotherapy Resistance In Ovarian Cancer
9/18/2011
For patients with ovarian cancer and their physicians, resistance to chemotherapy is a serious concern. However, researchers at Moffitt Cancer Center have identified a molecular pathway that may play a key role in the evolution of chemotherapy resistance...
Discovery Of Switch That Controls Stem Cell Pluripotency
9/18/2011
Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single event in a process called alternative splicing. Alternative splicing allows one gene to generate many different genetic messages and protein products...
Treating Glioblastoma By Starving Cancer Cells Of Cholesterol
9/18/2011
A new study suggests that blocking cancer cells' access to cholesterol may offer a new strategy for treating glioblastoma, the most common and deadly form of brain cancer, and perhaps other malignancies. The potential treatment could be appropriate for tumors with a hyperactive PI3K signaling pathway, which accounts for up to 90 percent of glioblastomas cases...