During Metamorphosis Nuclear Receptors Battle It Out In New Fruit Fly Model
10/09/2011
Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes as once thought. In fact, it only activates genes, and it is out-competed by a heme-binding receptor to repress the same genes during the larval to pupal transition in the fruit fly...
Brain Tumors Made More Aggressive By Dioxin-Like Chemical Messenger
10/09/2011
A research alliance of Heidelberg University Hospital and the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), jointly with colleagues of the Helmholtz Center for Environmental Research in Leipzig, have discovered a new metabolic pathway which makes malignant brain tumors (gliomas) more aggressive and weakens patients' immune systems...
In cancer, genes turn on and off at the wrong times, proteins aren't folded properly, and cellular growth and proliferation get out of control. Even a cancer cell's metabolism goes haywire, as it loses the ability to appropriately sense nutrients and use them to generate energy...
Incompatible Assumptions Common In Biomedical Research
10/09/2011
Strong, incompatible views are common in biomedicine but are largely invisible to biomedical experts themselves, creating artificial barriers to effective modeling of complex biological phenomena...
How PSA Test Helped Me - A Personal Story
10/08/2011
Just over three years ago I went to have a normal check up, which included a (prostate-specific antigen) PSA test. The doctor noticed that it was a slightly higher than it should be for a man of my age at the time, 53 years. Everything else came out OK - all other tests and physical examinations detected nothing...
How PSA Test Helped Me - A Personal Story
10/08/2011
Just over three years ago I went to have a normal check up, which included a (prostate-specific antigen) PSA test. The doctor noticed that it was a slightly higher than it should be for a man of my age at the time, 53 years. Everything else came out OK - all other tests and physical examinations detected nothing...
Cialis Gets FDA Green Light For Enlarged Prostate Treatment
10/08/2011
The FDA announced that it has approved Eli Lily's answer to Viagra, known as Cialis, for the treatment of enlarged prostate. This should prove to be a boon for Eli Lily's blockbuster impotence medication...
Bone Marrow Cells Can Slow Down Tumor Growth
10/08/2011
The November issue of The American Journal of Pathology published findings on a study that examined how bone marrow-derived cells (BDMCs), i.e. cells that are involved in the growth and spread of breast, lung, brain and stomach tumors, could be used in order to track their migration during the formation and expansion of tumors. The study was conducted in a mouse model developed by the researchers...
Cialis Gets FDA Green Light For Enlarged Prostate Treatment
10/08/2011
The FDA announced that it has approved Eli Lily's answer to Viagra, known as Cialis, for the treatment of enlarged prostate. This should prove to be a boon for Eli Lily's blockbuster impotence medication...
Eli Lilly and Company (NYSE: LLY) announced that the U.S. Food and Drug Administration (FDA) has approved Cialis® (tadalafil) tablets for once daily use for the treatment of men who have both erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia (ED+BPH)...