Mutations Causing CDA II Tracked Back To The Roman Empire
10/10/2011

Many of you might know that Congenital Dyserythropoietic Anemia type II (CDA II) is a rare blood disorder, due to a failure in final part of erythropoiesis. What will surprise you is the fact that some mutations responsible for the disease can be tracked 3.000 years back. A study led by the ENERCA member Prof...

To Slow Rates Of HIV And HPV Transmission In South Africa, Earlier Circumcision In Males May Be Effective Intervention
10/10/2011

According to Anna R. Giuliano, Ph.D., program leader in cancer epidemiology at Moffitt Cancer Center in Tampa, Fla., and colleagues in the Netherlands, earlier circumcision of males in South Africa may be a positive step in slowing the spread of both HIV and the human papillomavirus (HPV)...

First COX-2-Targeted PET Imaging Agent Offers New View Of Inflammation, Cancer
10/10/2011

A series of novel imaging agents could make it possible to "see" tumors in their earliest stages, before they turn deadly. The compounds, derived from inhibitors of the enzyme cyclooxygenase-2 (COX-2) and detectable by positron emission tomography (PET) imaging, may have broad applications for cancer detection, diagnosis and treatment...

Researchers Report Progress On Compound To Treat Neurological Diseases
10/10/2011

Results of a study by a group of University of Notre Dame researchers represent a promising step on the road to developing new drugs for a variety of neurological diseases...

Bone Marrow Cells Migrate To Tumors And Can Slow Their Growth
10/10/2011

Bone marrow-derived cells (BMDCs) participate in the growth and spread of tumors of the breast, brain, lung, and stomach. To examine the role of BMDCs, researchers developed a mouse model that could be used to track the migration of these cells while tumors formed and expanded...

Mine-Hunting Software Helping Doctors To Identify Rare Cells In Human Cancer
10/10/2011

Medical researchers are demonstrating that Office of Naval Research (ONR)-funded software developed for finding and recognizing undersea mines can help doctors identify and classify cancer-related cells. "The results are spectacular," said Dr. Larry Carin, professor at Duke University and developer of the technology. "This could be a game-changer for medical research...

Liver Cancer Decreasing In High Risk Countries, Increasing In Low Risk Countries
10/10/2011

A new study finds liver cancer incidence rates continue to increase in some low-risk parts of the world such as North America, and are decreasing in some of the highest risk countries of Asia. Despite this, the incidence rates in Asian countries remain twice as high as those in Africa and more than four times as high as rates in North America...

Small Molecules Can Starve Cancer Cells
10/10/2011

All cells in our body have a system that can handle cellular waste and release building blocks for recycling. The underlying mechanism is called autophagy and literally means "self-eating". Many cancer cells have increased the activity of this system and the increased release of building blocks equip the cancer cells with a growth advantage and can render them resistant towards treatment...

Pain From Chemotherapy Drugs Could Be Eased By Component In Marijuana
10/10/2011

A chemical component of the marijuana plant could prevent the onset of pain associated with drugs used in chemotherapy, particularly in breast cancer patients, according to researchers at Temple University's School of Pharmacy...

Bone Marrow Cells Can Slow Down Tumor Growth
10/09/2011

The November issue of The American Journal of Pathology published findings on a study that examined how bone marrow-derived cells (BDMCs), i.e. cells that are involved in the growth and spread of breast, lung, brain and stomach tumors, could be used in order to track their migration during the formation and expansion of tumors. The study was conducted in a mouse model developed by the researchers...