Mechanism Of Lung-Cancer Drug Resistance Revealed By Study
1/23/2012
New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs. The study was led by investigators with the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J...
By Stifling Protective Genes, Inflammatory Mediator Promotes Colorectal Cancer
1/23/2012
Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today in the advance online publication of the journal Nature Medicine...
Luteolin, A Plant Flavonoid, Blocks Cell Signaling Pathways In Colon Cancer Cells
1/23/2012
Luteolin is a flavonoid commonly found in fruit and vegetables. This compound has been shown in laboratory conditions to have anti-inflammatory, anti-oxidant and anti-cancer properties but results from epidemiological studies have been less certain...
Potential Key To Immune Suppression In Cancer Revealed By Study
1/23/2012
In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla...
Novel Imaging Platform Enables Researchers To Engineer A Switch To Tame Aggressive Cancers
1/23/2012
When cancers become aggressive and spread they are the most deadly. Unfortunately, little is known about how to stop this development. A new imaging platform developed by Lawson Health Research Institute's Drs. Ann Chambers and John Lewis is providing insight into just that - the exact moment when cancer cells turn deadly...
How Protein In Teardrops Annihilates Harmful Bacteria
1/23/2012
A disease-fighting protein in our teardrops has been tethered to a tiny transistor, enabling UC Irvine scientists to discover exactly how it destroys dangerous bacteria. The research could prove critical to long-term work aimed at diagnosing cancers and other illnesses in their very early stages...
Chemists Unlock Potential Target For Drug Development
1/23/2012
A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists. A team led by Dana Spence of MSU's Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1...
Mechanism Of Lung-Cancer Drug Resistance Revealed By Study
1/23/2012
New research published in Nature Medicine indicates that targeted drugs such as gefitinib might more effectively treat non-small cell lung cancer if they could be combined with agents that block certain microRNAs. The study was led by investigators with the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J...
Discovery Of High Risk Oesophageal Cancer Gene
1/22/2012
New research from Queen Mary, University of London has uncovered a gene which plays a key role in the development of oesophageal cancer (cancer of the gullet). The researchers studied families who suffer a rare inherited condition making them highly susceptible to the disease and found that a fault in a single gene was responsible...
In Patients With Rare Brain Tumor, Abnormal Chromosome Indicator Of Treatment And Outcome
1/22/2012
A recent analysis of clinical trial results performed by the Radiation Therapy Oncology Group (RTOG) demonstrate that a chromosomal abnormality - specifically, the absence (co-deletion) of chromosomes 1p and 19q - have definitive prognostic and predictive value for managing the treatment of adult patients with pure and mixed anaplastic oligodendrogliomas...