Elderly Cancer Patients Benefit From Immunotherapy
4/17/2012
Cancer is much more likely in the elderly than the young, and their bodies often are less prepared to fight the disease and the often-toxic side effects of treatment...
Breast Cancer Study Uncovers New Type Of Mutation
4/17/2012
Mayo Clinic researchers have discovered a new class of molecular mutation in various forms of breast cancer, a finding that may shed new light on development and growth of different types of breast tumors. Called fusion transcripts, the mutated forms of RNA may also provide a way to identify tumor subtypes and offer new strategies to treat them, investigators say...
Colon Cancer - New Mechanism Discovered
4/16/2012
Researchers from the Case Western Reserve University School of Medicine have discovered a new mechanism by which colon cancer develops. Whilst concentrating on 'junk DNA' i.e. DNA segments located between genes, the team found a set of master switches (gene enhancer elements) that turn key genes on and off. An alteration in the expression of these genes leads to colon cancers...
Ovarian Cancer - Using Genetics To Predict Chemotherapy Response
4/16/2012
According to the April 13 issue of the Journal of the National Cancer Institute, whether or not first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients can now potentially be established by using a DNA repair pathway-focused score. Most ovarian cancers are diagnosed when the disease is already in an advanced stage, i.e. stage III and IV...
Aggressive Prostate Cancer Risk Linked With Two Genetic Deletions In Human Genome
4/16/2012
According to a study published online in Proceedings of the National Academy of Sciences (PNAS), researchers have identified two inherited-genetic deletions in the human genome associated to the development of prostate cancer...
HIV-Positive Females Have High Anal Cancer Rates
4/16/2012
A new study by researchers at Montefiore Medical Center reveals that the incidence of anal carcinoma (AC) is increasing among HIV-positive women. The study entitled "High Prevalence of High Grade Anal Intraepithelial Neoplasia in HIV-Infected Women Screened for Anal Cancer" will appear in the Journal of Aids on May 1st, and was conducted from March 2008 to December 2010. Mark H...
Some Leukemia Patients Benefit From Chemotherapy
4/16/2012
An international study published in the April 12 issue of the New England Journal of Medicine reports that bone marrow transplants are not the best option for some young patients with acute lymphoblastic leukemia (ALL) who fail to achieve clinical remission following their induction therapy of intense chemotherapy...
Biomarkers May Predict Chemo-Resistant Breast Cancers
4/16/2012
Researchers at the University of Hull in the UK have identified a family of proteins that could potentially be used as biomarkers to predict resistance to chemotherapy in estrogen receptor-positive (ER-positive) breast cancer patients...
Blood Type A May Predispose To Some Rotavirus Infections
4/16/2012
Whether you become infected by some strains of rotavirus may depend on your blood type...
Predicting Chemotherapy Response In Ovarian Cancer Patients Via DNA Repair Pathway Score
4/16/2012
A DNA repair pathway-focused score has the potential to help determine if first-line platinum based chemotherapy can benefit advanced-stage ovarian cancer patients, according to a study published in the Journal of the National Cancer Institute. Most ovarian cancer patients are diagnosed with advanced disease (stages III and IV)...