Bevacizumab Doesn't Improve Survival In Some Older Lung Cancer Patients
4/17/2012
A study published in the April 18 issue of JAMA, reveals that Medicare insured non-small cell lung cancer (NSCLC) patients aged 65+, who received bevacizumab, in addition to the standard chemotherapy regimen carboplatin and paclitaxel, did not have improved survival compared to patients who received carboplatin and paclitaxel alone...
Small-Bowel Obstruction Post-Surgery, Risk Factors Examined
4/17/2012
A study in the April issue of Archives of Surgery, demonstrates that in comparison with laparoscopic surgery, open surgery seems to be linked to a higher risk of small-bowel obstruction (SBO). The researchers state in their study background that SBO is a common reason for emergency admission...
Altering Tumor Microenvironment Shown To Boost Response To Cancer Drugs During Live Imaging
4/17/2012
It should be possible to significantly improve the response of common cancers to existing "classical" chemotherapy drugs, say scientists at Cold Spring Harbor Laboratory (CSHL), by introducing agents that alter the interaction of cancer cells with their immediate surroundings, called the tumor microenvironment...
News From The Journal Of Clinical Investigation: April 16, 2012
4/17/2012
AUTOIMMUNITY Understanding bone loss in rheumatoid arthritis patients Rheumatoid arthritis causes joint stiffness and pain for over 2 million Americans. The disease is caused by an errant attack on healthy tissue by the body's immune system...
Potential New Treatment For Kidney Cancer By Specific Inhibition Of Autophagy
4/17/2012
New research at the University of Cincinnati (UC) suggests that kidney cancer growth depends on autophagy, a complex process that can provide cells with nutrients from intracellular sources. Researchers say in certain circumstances autophagy can protect tumor cells from chemotherapy, allowing them to survive for long periods of time in a hidden, dormant, metastatic state...
New Prostate Cancer Ultrasound Treatment Shows Promise
4/17/2012
A new experimental treatment for localized prostate cancer that uses high intensity focused ultrasound (HIFU) promises to be more effective and have fewer side effects than conventional treatments, according to a new study published early online in The Lancet Oncology on Tuesday...
'Addiction' Of Leukemia Cells Exploited In New Therapy
4/17/2012
A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules...
Valid Therapeutic Target Identified In Acute Myeloid Leukemia
4/17/2012
Through a groundbreaking new gene sequencing technology, researchers have demonstrated that the gene FLT3 is a valid therapeutic target in Acute Myeloid Leukemia, AML, one of the most common types of leukemia. The technique, developed by Pacific Biosciences, allows for the rapid and comprehensive detection of gene mutations in patients with AML...
Nanoparticles Home In On Brain Tumors, Boost Accuracy Of Surgical Removal
4/17/2012
Like special-forces troops laser-tagging targets for a bomber pilot, tiny particles that can be imaged three different ways at once have enabled Stanford University School of Medicine scientists to remove brain tumors from mice with unprecedented accuracy...
3-D RNA Modeling Opens Scientific Doors
4/17/2012
In a paper published in the journal Nature Methods, a team from the University of North Carolina at Chapel Hill demonstrates a simple, cost-effective technique for three-dimensional RNA structure prediction that will help scientists understand the structures, and ultimately the functions, of the RNA molecules that dictate almost every aspect of human cell behavior...