Promising Results In Three Ongoing Breast Cancer Trials
11/05/2012
A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial. "The bold long-term goal is a short-term oral treatment that prevents breast cancer by killing the precursor cells that initiate breast cancer," says Lance Liotta, co-director of Mason's Center for Applied Proteomics and Molecular Medicine (CAPMM)...
Pradaxa (Dabigatran) Bleeding Rates No Higher Than Warfarin, Says FDA
11/05/2012
Bleeding rates linked to new use of Pradaxa (Dabigatran) are no higher than they are with new users of warfarin, says a new FDA Drug Safety communication report update (November 2, 2012). The FDA (Food and Drug Administration) carried out an evaluation on Pradaxa after receiving several post-marketing reports of bleeding among new users...
Feedback Loop Maintains Basal Cell Population
11/05/2012
Notch - the protein that can help determine cell fate - maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein - TGF beta (transforming growth factor beta), said Baylor College of Medicine researchers in the journal Cell Stem Cell...
New Computer Program Improves Genetic Test Results For Lynch Syndrome
11/05/2012
Many patients who have genetic testing for Lynch syndrome, a hereditary predisposition to colon cancer, receive the inconclusive result "variants of uncertain clinical significance...
DNA Damage Repair: A Protein's Role
11/05/2012
In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors. The research appeared online in the Proceedings of the National Academy of Sciences (PNAS) Early Edition...
Discovery Of Gene Switch Important In Cancer Development
11/05/2012
Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer...
New Diagnostic Tool Could Lower Numbers Of Unnecessary Lymph Node Surgeries In Breast Cancer
11/05/2012
Using advanced microscopes equipped with tissue-penetrating laser light, cancer imaging experts at Johns Hopkins have developed a promising, new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread...
Pradaxa (Dabigatran) Bleeding Rates No Higher Than Warfarin, Says FDA
11/04/2012
Bleeding rates linked to new use of Pradaxa (Dabigatran) are no higher than they are with new users of warfarin, says a new FDA Drug Safety communication report update (November 2, 2012). The FDA (Food and Drug Administration) carried out an evaluation on Pradaxa after receiving several post-marketing reports of bleeding among new users...
Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children...
Patients With Deadliest Of Brain Cancers Benefit From Repeated Surgeries
11/03/2012
People who undergo repeated surgeries to remove glioblastomas - the most aggressive and deadliest type of brain tumors - may survive longer than those who have just a one-time operation, new Johns Hopkins research suggests. Glioblastoma, the brain cancer that killed Sen. Edward Kennedy, inevitably returns after tumor-removal surgery, chemotherapy, and/or radiation...