Research, led by Lori Hart, Ph.D., research associate and Constantinos Koumenis, Ph.D., associate professor,and research division director in the Department of Radiation Oncology, both from the Perelman School of Medicine, University of Pennsylvania, and Davide Ruggero, Ph.D...
Early Events In Cellular Aging Reveal How Lifestyle and Diet Affect Lifespan
11/26/2012
By experimenting on yeast, two scientists in the US have for the first time identified key events that occur early in the aging process of cells that may explain how genes and environmental factors like lifestyle and diet, interact to influence lifespan, aging, and age-related diseases like cancer...
In Phase 3 International Trial New Drug Overcomes Resistance In Patients With Rare Sarcoma
11/26/2012
A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber Cancer Institute who led the worldwide clinical trial...
Kidney Tumors May Be Smarter Than We Thought
11/26/2012
New research has found there are several different ways that kidney tumours can achieve the same result - namely, grow. Scientists have been trying to figure out how different people have kidney tumours with the same histology, or shape, although the genetic changes can vary among individual tumours...
Research Programme Offers Flower Power To Purge Poison And Produce Platinum
11/26/2012
A consortium of researchers led by WMG at the University of Warwick are to embark on a 3 million pound research programme called "Cleaning Land for Wealth" (CL4W), that will use a common class of flower to restore poisoned soils while at the same time producing perfectly sized and shaped nano sized platinum and arsenic nanoparticles for use in catalytic convertors, cancer trea...
Study Pinpoints New Targets For Ovarian Cancer Treatment
11/25/2012
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease...
For the first time, scientists at Fred Hutchinson Cancer Research Center have defined key events that take place early in the process of cellular aging...
Scientists Identify Potential Drug Target For Inflammatory Diseases Including Cancers
11/25/2012
A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes...
Cancer Treatment Could Be Improved By Discovery Of Drug Resistance Biomarker
11/25/2012
Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published by Cell Press in the journal Cell...
Reintroducing MiR-200c To Triple-Negative Breast Cancer Cells Makes Migrating Cells Self-Destruct
11/25/2012
Epithelial cells are homebodies - they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they have to leave their homes and to survive while traveling they must resist anoikis - like a third-grader at sleep-away camp...