Clinical Trials Do Not Show Complete Picture In Risk Of Hemorrhage From Warfarin
11/28/2012
Rates of hemorrhage for older patients on warfarin therapy are much higher than rates reported in clinical trials, found a study published in CMAJ (Canadian Medical Association Journal)...
News From The Journal Of Clinical Investigation: Nov. 26, 2012
11/27/2012
Parallel structure: Surprising similarities between kidney cells and neurons The primary function of the kidneys is to filter the blood to remove waste and retain blood cells and proteins. Podocytes are specialized kidney cells that form a filtering structure known as a slit diaphragm...
A team of researchers at McGill University have discovered a molecular basis for the potential cancer preventive effects of vitamin D. The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine's Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC...
Cervical Cancer Detection May Be Improved By Complementary New Test
11/27/2012
Routine smear tests have considerably reduced the number of cases of cervical cancer, but despite intensive screening 250 women in Sweden still die from the disease every year. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have developed new methods of minimising the number of missed cases and making diagnosis more reliable...
New Molecular Culprit Linked To Breast Cancer Progression
11/27/2012
Johns Hopkins researchers have uncovered a protein "partner" commonly used by breast cancer cells to unlock genes needed for spreading the disease around the body. A report on the discovery, published on the website of the Proceedings of the National Academy of Sciences, details how some tumors get the tools they need to metastasize...
Improving Life-Saving Blood Transfusions For Preterm Babies
11/27/2012
Results of new research from the University of Adelaide are a promising step forward in helping to improve the quality of life-saving blood transfusions for preterm babies, by reducing the likelihood of adverse inflammatory responses to the blood. Blood transfusions are among the most common medical procedures experienced by preterm babies, who are often anemic and suffer blood loss...
Cervical Cancer Detection May Be Improved By Complementary New Test
11/27/2012
Routine smear tests have considerably reduced the number of cases of cervical cancer, but despite intensive screening 250 women in Sweden still die from the disease every year. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have developed new methods of minimising the number of missed cases and making diagnosis more reliable...
New Treatment For Deadly Cancer Ewing Sarcoma
11/27/2012
A new medication for a deadly cancer called Ewing sarcoma, a rare disease where cancer cells are present in bones of soft tissue and is mostly found in children and young adults, has been discovered by experts from Huntsman Cancer Insititute (HCI) at the University of Utah and published in the journal Oncogene. Stephen Lessnick M.D., Ph.D...
Anticancer Virus As Brain Cancer Therapy
11/27/2012
Doctors now use cancer-killing viruses to treat some patients with lethal, fast-growing brain tumors. Clinical trials show that these therapeutic viruses are safe but less effective than expected. A new study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J...
Newly Discovered Effects Of Vitamin D On Cancer
11/27/2012
Vitamin D slows the progression of cells from premalignant to malignant states, keeping their proliferation in check A team of researchers at McGill University have discovered a molecular basis for the potential cancer preventive effects of vitamin D...