Breakthrough Personalised Medicine Xalkori® (Crizotinib) Launched For Lung Cancer
12/05/2012
Xalkori® (crizotinib) launched in UK for patients with previously treated ALK-positive advanced non-small cell lung cancer (NSCLC) Pfizer Limited has announced that Xalkori (crizotinib), the first of a new class of therapy for a type of lung cancer is now available in the UK...
News From The Annals Of Internal Medicine: Dec. 4, 2012
12/05/2012
Computer Alerts to Health Care Providers Improve Patient Outcomes in HIV Interactive computer alerts to warn health care providers of virologic failure improve patient outcomes in HIV. Health care information technology can be used to improve quality and safety of health care, yet such clinical decision-support systems (CDSS) are lacking in HIV care...
Making Shift Work Safer
12/05/2012
An international team of sleep researchers has developed the world's first screening tool to help reduce workplace accidents and illnesses, including cardiovascular disease and cancer, caused by shift work. Published in the journal Sleep, the new tool will enable health professionals and industry to better understand individual vulnerability to the health and safety impacts of shift work...
Prostate Cancer Drug Shows Promise In Triple-Negative And Estrogen-Positive Breast Cancer
12/05/2012
Breast cancers are defined by their drivers - estrogen and progesterone receptors (ER and PR) and HER2 are the most common, and there are drugs targeting each. When breast cancer has an unknown driver, it also has fewer treatment options - this aggressive form of breast cancer without ER, PR or HER2, which was thought not to be driven by hormones, is known as triple negative...
Women With Polycystic Ovary Syndrome On Combined Pill At Double The Risk For Blood Clots
12/05/2012
Women with polycystic ovary syndrome (PCOS) who are taking combined oral contraceptives have a 2-fold risk of blood clots compared with women without the disorder who take contraceptives, states a study published in CMAJ (Canadian Medical Association Journal)...
Fruit Flies Reveal Steps In Cancer Cell Development
12/04/2012
Using fruit flies as a model, researchers in Spain believe they have uncovered the individual steps that normal cells go through when they become cancerous and spread...
News From The Journal Of Clinical Investigation: Dec. 3, 2012
12/04/2012
Researchers inhibit plaque formation in a mouse model of Alzheimer's disease Alzheimer's disease is characterized by the accumulation of protein plaques in the brain. The plaques are generated by BACE1-mediated cleavage of the β-amyloid precursor protein...
With the X-ray vision of DESY's light source DORIS, a research team from Hamburg and Iceland has uncovered the molecular structure of a master regulator central to the most deadly form of skin cancer, melanoma...
Radiation Targeting Resistant Pockets As They Develop In Metastatic Lung Cancer Extends Survival
12/04/2012
The central skill of cancer is its ability to mutate - that's how it became cancerous in the first place. Once it's started down that path, it's not so difficult for a cancer cell to mutate again and again. This means that different tumors within a single patient or even different areas within the same cancerous deposit may develop different genetic characteristics...
A Mechanism Identified For The Transformation Of Colon Polyps
12/04/2012
Researchers from the University of Geneva demonstrate that, in this type of lesion, the rate of progression from a precancerous state to the tumor stage accelerates over time The causes underlying the development of certain types of common cancers have not yet been elucidated...