Chromosome-Capping Telomeres A Potential Target For Anti-Cancer Drugs
1/22/2013
Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural and mechanical properties of telomeres that could help guide the development of new anti-cancer drugs...
Computerized Tool And Simple Blood Test Can Help Identify Trauma Patients At Greatest Risk Of Death
1/22/2013
A study of more than 9,500 patients discovered that some trauma patients are up to 58 times more likely to die than others, regardless of the severity of their original injuries. The Intermountain Medical Center research study of more than 9,500 patients discovered that some trauma patients are up to 58 times more likely to die than others, regardless of the severity of their original injuries...
Cancer Death Rates Dropping Significantly
1/21/2013
The overall rate of cancer mortality has fallen 20 percent since 1991, according to new figures released by the American Cancer Society's annual Cancer Statistics report. Since 1991, the rate of cancer mortality has declined from 215.1 per 1000 to a little over 173 in 2009...
Quadruple Helix DNA Exists In Human Genome
1/21/2013
60 years after Cambridge researchers Watson and Crick published their discovery of "double helix" DNA, the molecule of life, another team at the same UK university has published proof that four-stranded "quadruple helix" DNA also exists within the human genome...
One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become resistant to treatment, and median survival of patients is only about 15 months...
Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms are sensitive - and thus vulnerable - to a novel cancer stem cell-targeting drug currently under development...
New Insights On Leukemia From Study Of Cancer Cell Metabolism
1/21/2013
University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have a much slower metabolism than most other tumors cells...
Grape Seed Extract Effective In Colorectal Cancer Treatment
1/21/2013
Grape seed extract is effective in inhibiting the growth of colorectal cancer cells, researchers from the University of Colorado Cancer Center reported in the journal Cancer Letters. In fact, the more advanced the colorectal cancer cells are, the more grape seed extract stops their growth and survival, the authors added...
Researchers See In Real-Time The Earliest Molecular Stages Of Cancer And Aging In Luminescent Mice
1/21/2013
In a study published in the journal Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth in mice using a gene closely linked to these processes...
The Importance Of Autophagy Regulation
1/21/2013
Researchers at the University of California, San Diego School of Medicine have identified a molecular mechanism regulating autophagy, a fundamental stress response used by cells to help ensure their survival in adverse conditions. The findings are published online in the journal Cell...