American College Of Physicians Releases New Prostate Cancer Screening Guidance Statement
4/08/2013
Shared-decision making, clear patient preference recommended before PSA testing Men between the ages of 50 and 69 should discuss the limited benefits and substantial harms of the prostate-specific antigen (PSA) test with their doctor before undergoing screening for prostate cancer, according to new recommendations issued today by the American College of Physicians (ACP)...
Research Letter, Viewpoint, Invited Commentary Examine Cervical Cancer Screening Intervals
4/08/2013
JAMA Internal Medicine Study Highlights A research letter by Zahava Berkowitz, M.S.P.H., M.Sc., of the Centers for Disease Control and Prevention, and colleagues found that most of the 2,087 primary care clinicians surveyed recommended Papanicolaou (pap) tests sooner than recommended by guidelines after co-testing for the human papillomavirus (HPV)...
Personalized Ovarian Cancer Vaccine Shows Promise In Trial
4/08/2013
Delegates at a conference in the US this week are hearing about early results of a trial of a new personalized ovarian cancer vaccine that offers new hope for the large number of patients who relapse after treatment...
Common Heart Drug Associated With Increased Cancer Risk
4/08/2013
A drug known as amiodarone, used to treat heartbeat irregularities, could raise a person's cancer risk, according to new research published in the journal Cancer. The study reveals that the risk, which the investigators described as "borderline significantly increased", is more prevalent in men and people who take greater doses of amiodarone...
In An Animal Model Of Ovarian Cancer, Engineered T Cells Kill Tumors But Spare Normal Tissue
4/08/2013
The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal immune response against cancer. Identifying which antigens a patient's tumor cells express is the cornerstone of designing cancer therapy for that individual...
Women with HIV acquire cancer-causing forms of the human papillomavirus (HPV) that are not included in the current HPV vaccines Gardasil and Cervarix, according to new research from Fox Chase Cancer Center presented at the AACR Annual Meeting 2013 on Sunday, April 7...
Scientists have shed light on a common bleeding disorder by growing and analysing stem cells from patients' blood to discover the cause of the disease in individual patients. The technique may enable doctors to prescribe more effective treatments according to the defects identified in patients' cells...
Arrhythmia Drug May Increase Cancer Risk
4/08/2013
One of the most widely used medications to treat arrhythmias may increase the risk of developing cancer, especially in men and people exposed to high amounts of the drug. That is the conclusion of a new retrospective study published early online in CANCER, a peer-reviewed journal of the American Cancer Society...
Adult Stem Cells Isolated From Human Intestinal Tissue For The First Time
4/08/2013
For the first time, researchers at the University of North Carolina at Chapel Hill have isolated adult stem cells from human intestinal tissue. The accomplishment provides a much-needed resource for scientists eager to uncover the true mechanisms of human stem cell biology...
Scientists Describe The Mechanics Of Oncogene-Induced Senescence
4/08/2013
Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides - the building blocks of DNA molecules - cells can suppress cancer development by forcing a damaged cell into a senescent state, where the cell remains alive yet cannot reproduce...