Inhibiting Growth Of Triple-Negative Breast Cancer With Omega-3 Fatty Acids
4/11/2013
Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively than cells from luminal types of the disease...
During Pregnancy, Excess Estrogen Can Silence BRCA1 In Daughters, Increasing Breast Cancer Risk
4/11/2013
Excess estrogen levels during pregnancy can disable, in their daughters, a powerful breast cancer tumor suppressor gene, say researchers at Georgetown Lombardi Comprehensive Cancer Center. They found the DNA repair gene BRCA1 to be silenced in one year-old girls exposed to a high hormonal fetal environment...
A variety of mutations may give rise to breast cancer, but scientists generally assume that it starts off with just a few. That's because later-stage breast cancers tend to have more mutations - they are more heterogeneous - than early stage cancers...
Critical Metabolic Alterations Identified In Triple-Negative Breast Cancer Cells
4/11/2013
Researchers at Fox Chase Cancer Center have identified a host of small molecules critical to metabolism in cells of triple-negative breast cancer - one of the least understood groups of breast cancer. These molecules, called metabolites, include key players in energy regulation and lipid synthesis...
Study Finds Bird Virus Promising For Prostate Cancer Treatment
4/11/2013
A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans. Researchers have discovered that a genetically engineered Newcastle disease virus, which harms chickens but not humans, kills prostate cancer cells of all kinds, including hormone-resistant cancer cells. The work of Dr...
Endometriosis Treatments Lower Ovarian Cancer Risk
4/11/2013
A novel study shows women who undergo surgical treatment for endometriosis have a lower risk of developing ovarian cancer. According to results published in Acta Obstetricia et Gynecologica Scandinavica, a journal of the Nordic Federation of Societies of Obstetrics and Gynecology, hormonal treatments for endometriosis did not lower ovarian cancer risk...
FDA Step Closer To Approving Breast Cancer Drug "Palbociclib"
4/11/2013
The pharmaceutical giant Pfizer has just announced that their drug "Palbociclib", a selective inhibitor of cyclin dependent kinases (CDK) 4 and 6, has just received Breakthrough Therapy designation by the United States Food and Drug Administration (FDA) for breast cancer treatment. Breast cancer is the most common cancer among women worldwide...
Fetal Exposure To Air Pollution Increases Risk Of Pediatric Cancers
4/10/2013
Pregnant women exposed to air pollution put their children at an increased risk of three different types of cancer, according to new research presented at the AACR Annual Meeting 2013. In their study, researchers identified that prolonged exposure to traffic-related air pollution can increase a child's risk of acute lymphoblastic leukemia and two other rare childhood cancers...
BIND Therapeutics' Nanoparticle Drug Effective Against Multiple Solid Tumors In Phase 1 Study
4/10/2013
The nanoparticle drug BIND-014 is effective against multiple solid tumors, according to results generated by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare, and presented at the American Association for Cancer Research (AACR) Annual Meeting 2013. Data for the study was generated at the Virginia G...
Clinical Trial Finds New Class Of Cancer Drugs Safe And Effective
4/10/2013
The safety and preliminary efficacy of a new class of tumor fighting drugs were reported by Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials and the Translational Genomics Research Institute (TGen)...