The malignant march of cancer cells slowed by thwarting protein production
7/22/2013
Protein production or translation is tightly coupled to a highly conserved stress response that cancer cells rely on for survival and proliferation, according to Whitehead Institute researchers...
Innovative technique can tell if drugs have hit their target in the human body
7/22/2013
The search for new drugs, including those for cancer, is set to speed up thanks to a new research technique invented by scientists at the Nanyang Technological University (NTU). Named the "Cellular Thermal Shift Assay" (CETSA), scientists can now know for sure if a drug had reached its target protein in the body, which is a critical step in determining the effectiveness of most medicines...
Compounds outsmart solid tumors' malfunctioning machinery
7/22/2013
Molecular biologists in the School of Medicine at The University of Texas Health Science Center San Antonio have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting effects. This machinery, the proteasome, is deregulated in cancer...
Breast cancer patients benefit from treatments tailored specifically for their tumor types
7/22/2013
The Side-Out Foundation's breast cancer pilot study, led by the Translational Genomics Research Institute (TGen), Translational Drug Development (TD2) and Scottsdale Healthcare, has shown that cancer patients do better when their treatment is guided by molecular profiling...
Cell phone game joins fight against cancer
7/21/2013
Anyone fancy a game of cancer hunting? The charity Cancer Research UK has announced a partnership with an England-based software agency to develop a game in which the general public can analyze cancer data while playing. Scientists hope the game will help them recognize new causes of cancer...
Brain tumor cells and blood vessels targeted by nano drug that can cross the blood-brain barrier
7/21/2013
An experimental drug in early development for aggressive brain tumors can cross the blood-brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James)...
Cell phone game joins fight against cancer
7/20/2013
Anyone fancy a game of cancer hunting? The charity Cancer Research UK has announced a partnership with an England-based software agency to develop a game in which the general public can analyze cancer data while playing. Scientists hope the game will help them recognize new causes of cancer...
Chemical contaminants in food evaluated by Danish survey
7/20/2013
In general, Danes have no reason to worry about unwanted chemical compounds in the food they put on their table - especially not if they eat a varied diet. However, a monitoring survey puts focus on certain compounds - e.g. inorganic arsenic and acrylamide, the intake of which should be reduced due to health risks...
Researcher finds way to convert blood cells into autoimmune disease treatment
7/19/2013
Cells from one's own blood could be converted into a treatment for autoimmune diseases, like rheumatoid arthritis and Crohn's disease, based on the discovery of a Purdue University researcher. Chang Kim, a professor of comparative pathobiology, has created a way to direct the differentiation of T-cells, a white blood cell that is a key player in the body's immune system...
Menopausal Hot Flashes More Frequent And Severe In Cancer Survivors
7/19/2013
Women who survive cancer have more frequent, severe, and troubling hot flashes than other women with menopausal symptoms, according to a study published online in Menopause, the journal of The North American Menopause Society (NAMS)...