Difference in breast cancer survival between black and white women has not changed substantially
7/23/2013
In an analysis of 5-year survival rates among black and white women diagnosed with breast cancer between 1991 and 2005, black women continued to have a lower rate of survival, with most of the difference related to factors including poorer health of black patients at diagnosis and more advanced disease, rather than treatment differences, according to a study in the July 24/31 issue of JAMA...
Research on cell-based therapy and cancer furthered by stem cell discovery
7/23/2013
Stem-cell researchers at UC San Francisco have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body...
Missing piece of pediatric cancer puzzle uncovered
7/23/2013
Most of the time, it takes decades of accumulating genetic errors for a tumor to develop. While this explains the general occurrence of cancer in adults, it leaves a gap in understanding of the cause of pediatric tumors. In a study published in the July issue of the Proceedings of the National Academy of Sciences, researchers found a missing piece of the pediatric cancer puzzle...
New drug treatment strategy may be effective in the deadliest cancers
7/23/2013
UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called "myc," paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments. Myc acts somewhat like a master switch within cells to foster uncontrolled growth. Until now, it has been impossible to target with drugs...
Absence of specific enzyme in cartilage can lead to benign tumors in mice
7/23/2013
Rhode Island Hospital researchers have found that the absence of the Shp-2 enzyme near specialized cartilage cells can lead to the development of multiple benign cartilage tumors in mice, a model that recapitulates the rare human tumor syndrome metachondromatosis. Shp2 is an enzyme in the cell that regulates the activity of other proteins and signaling pathways...
In EORTC trial for patients with desmoid-type fibromatosis, moderate dose radiotherapy effective
7/23/2013
A phase 2 EORTC trial for patients with inoperable desmoid-type fibromatosis has shown that moderate dose radiotherapy is an effective treatment for patients with such a rare type of tumor. The study results published in Annals of Oncology show that response after radiation therapy is slow, and that continuing regression is seen even after three years. Dr. Ronald B...
Time between cancer diagnosis and treatment provides 'window of opportunity' to optimize health
7/23/2013
For patients with cancer, "prehabilitation" - interventions given between the time of diagnosis and the start of treatment - has the potential to reduce complications from treatments and improve physical and mental health outcomes, according to a report in the August American Journal of Physical Medicine & Rehabilitation (AJPM&R)...
HPV linked to a third of throat cancers
7/22/2013
One third of people with cancers in the back of the throat (oropharyngeal cancers) are infected with a certain strain of human papillomavirus (HPV), according to new research published in the Journal of Clinical Oncology at the weekend...
Half a million UK cancer survivors faced with disability and poor health, UK
7/22/2013
At least one in four people living with cancer - over 500,000 in the UK[1] - experience a wide range of long-term debilitating health conditions caused by their cancer, according to a new report by Macmillan Cancer Support...
Proteomics can improve breast cancer treatment
7/22/2013
Researchers at Karolinska Institutet in Sweden have identified a protein that could help physicians decide what type of therapy patients with hormone driven breast cancer should go through...