Ovarian cancer sniffed out by dogs
8/11/2013
Researchers are looking to create a breakthrough method of detecting ovarian cancer - by using dogs to sniff out the disease. A group of researchers collaborated to investigate using canine olfaction and chemical and nanotechnology analysis as a means of detecting early-stage ovarian cancer...
A new study by thoracic surgeons and pathologists at Memorial Sloan-Kettering Cancer Center shows that a specific pattern found in the tumor pathology of some lung cancer patients is a strong predictor of recurrence. Knowing that this feature exists in a tumor's pathology could be an important factor doctors use to guide cancer treatment decisions...
Cancer cells hide from the immune system in tumor microenvironment
8/11/2013
Cancer progression is aided by the ability of tumors to evade recognition by the immune system. In this issue of the Journal of Clinical Investigation, Gerard Blobe and colleagues at Duke University identify a mechanism by which tumors evade detection...
Understanding how neurons move sheds light on how cancer cells invade healthy tissues
8/10/2013
The invasion of brain-tumor cells into surrounding tissue requires the same protein molecule that neurons need to migrate into position as they differentiate and mature, according to new research from the University of Illinois at Chicago College of Medicine and published in the online journal PLOS ONE...
In glioblastoma multiforme, cell maturity pathway is deleted or weak
8/10/2013
A program that pushes immature cells to grow up and fulfill their destiny as useful, dedicated cells is short-circuited in the most common and deadly form of brain tumor, scientists at The University of Texas MD Anderson Cancer Center report this week in the Early Edition of the Proceedings of the National Academy of Sciences (PNAS)...
Scientists identify key protein that modulates organismal aging
8/10/2013
Scientists at Sanford-Burnham Medical Research Institute have identified a key factor that regulates the autophagy process, a kind of cleansing mechanism for cells in which waste material and cellular debris is gobbled up to protect cells from damage, and in turn, modulates aging...
Leading bowel cancer charity launches new endoscopy guide
8/09/2013
Bowel Cancer UK, has launched a new information booklet which will inform and advise patients who have been referred by their GP for either a flexible sigmoidoscopy or colonoscopy. The guide discusses both procedures and also helps people understand what to expect and what choices they may have...
The genome of aggressive cervical cancer that killed Henrietta Lacks
8/09/2013
A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa...
Loss of microRNA decoy might contribute to development of soft-tissue sarcoma
8/09/2013
Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown...
Birthwort herb implicated in upper urinary tract cancers
8/09/2013
Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation...