Drug design to target cancer and inflammatory disease aided by chemists
8/12/2013
Chemists at Indiana University Bloomington have produced detailed descriptions of the structure and molecular properties of human folate receptor proteins, a key development for designing new drugs that can target cancer and inflammatory diseases without serious side effects...
Lymphoma 'triggered by immune-regulating molecules'
8/12/2013
Scientists have discovered that a small group of immune-regulating molecules could trigger lymphoma, according to a study published in the The Embo Journal. Researchers from The Scripps Research Institute (TSRI) in California have found that six microRNA molecules - short molecules found in nearly all animal and plant cells, may be responsible for lymphoma when overproduced...
Blocking DNA repair may fight therapy resistant leukemia
8/12/2013
New research posted online by the Nature journal Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance survival...
Improved survival for some Burkitt lymphoma patients
8/12/2013
Treatment advances have helped improve patient survival of Burkitt lymphoma, a highly aggressive cancer, but not among the elderly, patients at a late stage, or blacks. A new study, reported in the journal Cancer, uses those findings to develop a risk score that will help doctors, patients, families, and researchers better understand prognosis...
Spinal tumors: carbon ion radiotherapy 'safe and effective'
8/12/2013
Researchers have revealed that a specific radiation therapy is "safe and effective" in controlling cancer growth in patients with spinal tumors, as well as prolonging survival, according to the journal Cancer...
UNC-Malawi cancer pathology laboratory is a model for Sub-Saharan Africa
8/12/2013
Since 2011, the University of North Carolina has partnered with the government of Malawi to establish a pathology laboratory in the nation's capital, building on an existing decades-long collaboration...
New microfluidic chip can capture live tumor cells in the blood
8/12/2013
Tumor cells circulating within a patient's bloodstream can carry cancer from a primary tumor site to distant sites of the body, spreading the disease...
Typical protein profile of tumor cells decoded; 59 tumor cell lines investigated
8/12/2013
In what is the biggest study of its kind to date, researchers from Technische Universitat Munchen (TUM) have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular proteins," says Prof. Bernhard Kuster, Head of the TUM Chair of Proteomics and Bioanalytics...
Carbon ion radiotherapy safe and effective for treating inoperable spinal tumors
8/12/2013
A new analysis has found that a type of radiation therapy called carbon ion radiotherapy can control cancer growth and prolong survival in patients with spinal tumors. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that the treatment is a promising alternative for patients whose spinal tumors cannot be surgically removed...
Researchers discover how vitamin B12 is made
8/12/2013
A scientific breakthrough by researchers at the University of Kent has revealed how vitamin B12/antipernicious anaemia factor is made - a challenge often referred to as 'the Mount Everest of biosynthetic problems'. Vitamin B12 is pieced together as an elaborate molecular jigsaw involving around 30 individual components...