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Gene variant associated with increased risk and severity of nerve disorder linked to widely-prescribed cancer drug
2/26/2015

Children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug...

Study suggests need for more sensitive lung cancer screening criteria
2/26/2015

An analysis of lung cancer incidence and screening found a decline in the proportion of patients with lung cancer meeting high-risk screening criteria, suggesting that an increasing number of...

Findings may help with the management of anticoagulant-related bleeding within the brain
2/26/2015

Among patients with oral anticoagulation-associated intracerebral hemorrhage (bleeding within the brain), reversal of international normalized ratio (INR; a measure used to determine the clotting...

'Patchwork' ovarian cancer more deadly
2/26/2015

The most common type of ovarian cancer is more deadly if it consists of a patchwork of different groups of cells, according to a Cancer Research UK study published in PLOS Medicine*.

Tumor location in colorectal cancer may influence survival
2/26/2015

The two halves of the human colon have different embryonic origins and gene expression patterns, and these differences may also play a role in cancer biology, according to a study published in the...

Gene regulatory path revealed as target for therapy of aggressive pediatric brain cancer
2/26/2015

Laboratory studies suggest anticancer drug already in clinical trials in children may interrupt this gene pathwayWorking with cells taken from children with a very rare but ferocious form of...

'Patchwork' ovarian cancer more deadly
2/26/2015

The most common type of ovarian cancer is more deadly if it consists of a patchwork of different groups of cells, according to a Cancer Research UK study published in PLOS Medicine*.

Tumor location in colorectal cancer may influence survival
2/26/2015

The two halves of the human colon have different embryonic origins and gene expression patterns, and these differences may also play a role in cancer biology, according to a study published in the...

Androgen receptor abnormality may not be associated with primary resistance to taxane chemotherapy
2/26/2015

Findings from a small prospective study suggest that androgen receptor V7 (or AR-V7) status does not significantly affect response to taxane chemotherapy in men with metastatic castration-resistant...

MD Anderson studies skin cancer patients resistant to leading therapy
2/26/2015

Powerful drugs known as BRAF-inhibitors have been crucial for melanoma patients, saving lives through their ability to turn off the BRAF protein's power to spur cancer cell growth.