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T-cell receptor sequencing reveals novel biomarkers for ovarian cancer
6/07/2016

The ability of tumor-infiltrating lymphocytes (TILs) such as T cells to produce multitudes of clones that overwhelm and effectively control cancer cells has been demonstrated, but the significance...

Immunotherapy combination of nivolumab and ipilimumab shows promising tumour reduction in lung cancer
6/07/2016

Bristol-Myers Squibb has announced updated results from the CheckMate -012 study, a multi-arm, Phase Ib trial evaluating nivolumab alone or in combination with other therapies, in patients with...

UT Southwestern cancer researchers find up to one-quarter of lung cancer patients may be ineligible for immunotherapy
6/07/2016

A significant proportion of lung cancer patients also have autoimmune disease, which may make them unsuitable for increasingly popular immunotherapy treatments, a team of researchers at UT...

Does using biomarker to select patients for Phase 1 trials improve efficacy?
6/07/2016

Precision or personalized medicine is about selecting patients with a particular protein or genomic biomarker who might benefit from a specific therapy.

Do picture warnings on cigarettes increase quit attempts?
6/06/2016

Compared with text-only warnings, pictorial warnings on cigarette packages are more likely to encourage smokers to quit, new research shows.

Increase in obesity among pediatric hodgkin lymphoma patients may be linked to disease relapse
6/06/2016

Obesity has been identified as an adverse risk factor for survival in many adult and childhood cancers, but not in pediatric Hodgkin lymphoma, the most common cancer in adolescents.

Nivolumab extends survival for patients with advanced kidney cancer treated beyond disease progression
6/06/2016

In a large randomized study, the immunotherapy drug nivolumab, a checkpoint inhibitor, was shown to be a safe and effective therapy for kidney cancer even in patients who continued treatment after...

Giving chemotherapy after radiotherapy improves survival for patients with rare brain tumour
6/06/2016

Giving chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent.

Rucaparib shows clinical benefit in pancreatic cancer patients with BRCA mutation
6/06/2016

Results suggest a potential - and much-needed - treatment option for some pancreatic cancer patients.

New drug 'retrains' immune system to fight aggressive bladder cancer
6/06/2016

A new drug that harnesses the immune system to attack tumors is highly effective against advanced bladder cancer, according to the results of an international clinical trial presented at the annual...