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Single-lesion biopsy may be insufficient to choose therapy targeting resistance mutations
2/08/2016

When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to biopsy a single metastatic lesion to test for new mutations...

Possible marker for recurring HPV-linked oropharyngeal cancers
2/08/2016

A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in...

Cancer treatment: Therapeutic approach gives hope for the treatment of multiple myeloma
2/08/2016

A new therapeutic approach tested by a team from Maisonneuve-Rosemont Hospital (CIUSSS-EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a...

Protein that switches cancers from inflammation to proliferation identified
2/08/2016

Oxford University scientists researching PAD4, a protein that plays a role in the development of inflammatory diseases like arthritis and which is regularly found in cancers have uncovered the...

NIH researchers identify striking genomic signature shared by 5 types of cancer
2/08/2016

National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.

Gene family turns cancer cells into aggressive stem cells that keep growing
2/08/2016

An examination of 130 gene expression studies in 10 solid cancers has found that when any of four related genes is overexpressed, patients have much worse outcomes, including reduced survival.

Cancer treatment: Therapeutic approach gives hope for the treatment of multiple myeloma
2/08/2016

A new therapeutic approach tested by a team from Maisonneuve-Rosemont Hospital (CIUSSS-EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a...

Study compares effectiveness of phone-based and web-based smoking cessation programs in four states
2/08/2016

A new analysis indicates that states' Web-based and phone-based tobacco cessation programs can help people quit smoking, but certain personal characteristics may lead individuals to prefer one type...

Study compares effectiveness of phone-based and web-based smoking cessation programs in four states
2/08/2016

A new analysis indicates that states' Web-based and phone-based tobacco cessation programs can help people quit smoking, but certain personal characteristics may lead individuals to prefer one type...

Health-care disparities contribute to delayed testicular cancer diagnosis in a transgender woman
2/05/2016

A family physician reports the case of a transgender woman whose testosterone levels rose unexpectedly while on feminizing hormones, leading eventually to a diagnosis of a rare, virilizing form of...