Foundation Medicine identifies novel, clinically actionable gene fusion NTRK1 in lung cancer
10/30/2013
Foundation Medicine, Inc. (NASDAQ:FMI) has announced that the discovery of a novel and potentially clinically actionable oncogenic gene fusion in lung cancer, NTRK1, using FoundationOneTM, was published in the current online edition of Nature Medicine1...
Five commonly performed tests and treatments in pulmonary medicine may not always be necessary
10/30/2013
A list released on October 28th, identified five commonly performed tests and procedures in pulmonary medicine that may not always be necessary. The list, part of the ABIM Foundation's Choosing Wisely® campaign, was produced by a collaborative task force assembled by the American Thoracic Society (ATS) and the American College of Chest Physicians (ACCP)...
VisionGate's 3D imaging platform accurately detects lung cancer in sputum
10/30/2013
VisionGate, Inc., a company developing a revolutionary non-invasive test for the early detection of lung cancer, has reported clinical data showing that its automated 3D cell imaging platform, the Cell-CT™, can detect lung cancer in sputum samples with high sensitivity and specificity...
Possible resistance mechanisms of colorectal cancer to bevacizumab (Avastin)
10/30/2013
A University of Colorado Cancer Center study published in the journal PLOS ONE shows that when colorectal cancer is targeted by the drug bevacizumab (Avastin), tumors may switch dependence from VEGF-A, which is targeted by the drug, to related growth factors in including VEGF-C, VEGF-D and placental growth factor...
Suicide risk higher in youths with cancer diagnosis
10/30/2013
Receiving a cancer diagnosis is difficult to hear at any age, but new research suggests that teens and young adults who are diagnosed with the disease have an increased risk for suicide. Researchers say it could be related to their stress-coping strategies, which may not yet be fully developed...
2 related genes underlie the development of two rare bone tumours in nearly all patients
10/30/2013
Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes. These mutations are found in nearly 100 per cent of patients suffering from two rare bone tumours; chondroblastoma and giant cell tumour of the bone...
Mechanisms and potential biomarkers identified for tumor cell dormancy
10/30/2013
Oncologists have long puzzled over the fact that after cancer treatment, single cancer cells that are dispersed throughout the body - so-called disseminated tumor cells - are quick to grow and form secondary tumors called metastases in certain organs, while in other organs they metastasize more slowly, sometimes decades later...
South Asian-Canadians living in Peel Region may be 15 per cent less likely than other Ontarians to be screened for breast, cervical or colorectal cancer, making them much more vulnerable to cancer deaths. The findings were published in a report by researchers at the Centre for Research on Inner City Health. Peel Region - a municipality comprised of Brampton, Caledon and Mississauga - has 1...
Molecular switch targeted in malaria mosquitoes
10/30/2013
Half of the world's population is at risk of getting malaria - about 3.3 billion people - according to the World Health Organziation (WHO). And although prevention and control measures have led to a reduction in mortality rates, WHO estimates that 660,000 people died of this disease in 2010. Malaria is particularly prevalent in Africa's poorest countries...
Preliminary results find African-American women disadvantaged when it comes to HPV vaccines
10/30/2013
Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers at Duke Medicine...