Why combination drug treatment ineffective in cancer clinical trials
12/07/2013
Medical researchers at the University of Alberta have discovered that combination drug therapy didn't work well in clinical trials for cancer patients because one drug was making the other drug ineffective.
Researchers from the Fred Hutchinson Cancer Research Center in Seattle, WA have taken a closer look at existing mouse models of cancer, specifically comparing them to human cancer samples.
Genetic breast cancer screening may benefit those at intermediate risk
12/07/2013
Archimedes Inc., a healthcare modeling and analytics company, has announced results of a simulated clinical trial which found that the seven single-nucleotide polymorphisms (7SNP) genetic test for breast cancer was most cost effective when used to guide MRI screenings for patients found to have an intermediate lifetime risk of developing the disease.
Protein in prostate tissue 'indicates increased cancer risk'
12/06/2013
Researchers have discovered that men who have a specific protein present in prostate tissue biopsies may be at increased risk of developing prostate cancer. This is according to a study published in the Journal of Clinical Oncology.The American Cancer Society estimates that around 238,590 new cases of prostate cancer will have been diagnosed in the US throughout 2013.
Compression stockings viable as treatment for leg ulcers
12/06/2013
New research from the UK has shown that compression stockings are just as effective at treating venous leg ulcers as four-layer traditional bandages, promising cost savings for the National Health Service.
How brain cancer cells hide from drugs
12/06/2013
Researchers from UCLA's Jonsson Comprehensive Cancer Center (JCCC) have discovered a biological mechanism that allows brain tumor cells to escape from the drugs designed to target them, resulting in drug resistance. The study was published in the December 5, 2013 online issue of Science.Glioblastoma is the most common and deadliest form of brain cancer.
Cigarette smoking after cancer diagnosis increases risk of death
12/06/2013
Men who continued to smoke after a cancer diagnosis had an increased risk of death compared with those who quit smoking after diagnosis, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Therapeutic benefits of carbon monoxide for prostate, lung cancer
12/06/2013
In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.
Bone destruction in diseases such as arthritis and cancer: new target identified for prevention
12/06/2013
The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy bone. However, excessive osteoclast activity leads to bone destruction in skeletal diseases such as osteoporosis, rheumatoid arthritis and cancer metastases in bone.
Counting tumor-attacking immune cells to predict ovarian cancer survival
12/06/2013
One way to predict survival of many types of cancer is by counting the number of tumor-attacking immune cells that have migrated into the tumor in an effort to eradicate it - a sign of the body's immune response to the cancer. However, quantifying these armies of immune cells has been difficult - until now.