SIRT5 regulation has dramatic effect on mitochondrial metabolism
12/12/2013
The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study published in the journal Cell Metabolism, Buck Institute researchers have now identified widespread regulation of proteins involved in metabolism by the mitochondrial sirtuin, SIRT5.
Some older patients with breast cancer may avoid radiotherapy
12/12/2013
Omission of radiotherapy is a reasonable option for women age 65 or older who receive hormone therapy after breast-conserving surgery for hormone receptor-positive, axillary node-negative breast cancer, according to results of the PRIME 2 trial presented at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.
Breast cancer screening: benefit more consistent across studies than previously understood
12/12/2013
Re-examination of data from four large studies of the benefits and harms of mammography screening shows that the benefits are more consistent across these studies than previously understood and that all the studies indicate a substantial reduction in breast cancer mortality with screening, according to results presented at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.
Older breast cancer survivors benefit from exercise programs
12/12/2013
New research suggests that breast cancer survivors of an older age should follow ongoing exercise programs involving resistance and impact training to build and maintain muscle strength and bone density. This is according to a follow-up study published in The Journal of Cancer Survivorship.According to the American Cancer Society, there are more than 2.
Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue. The findings are the latest from the St.
New method devised to measure life's tugs and nudges
12/12/2013
As embryonic tissue develops, cells push and pull on each other, and they must do so correctly for the tissue to develop properly. Now scientists at Harvard University have devised the first method to measure these forces in three-dimensional (3D) tissues and living embryos.
Breast cancer: older survivors benefit from exercise programs
12/12/2013
New research suggests that breast cancer survivors of an older age should follow ongoing exercise programs involving resistance and impact training to build and maintain muscle strength and bone density. This is according to a follow-up study published in The Journal of Cancer Survivorship.According to the American Cancer Society, there are more than 2.
Evidence-based recommendations for platelet-rich plasma
12/12/2013
Platelet-rich plasma (PRP) has grabbed headlines in recent years for its role in helping some of sports' biggest stars return to play following injury - including golfer Tiger Woods, Super Bowl winner Hines Ward and NBA legend Kobe Bryant.
Blood clots seen to absorb bacterial toxin
12/12/2013
Blood clots play an unexpected role in protecting the body from the deadly effects of bacteria by absorbing bacterial toxins, researchers at the University of California, Davis, have found. The research was published in the journal PLoS ONE.
Tracking zinc in cells for prostate cancer diagnosis
12/11/2013
Scientists from the Massachusetts Institute of Technology have developed a new optical sensor that can track zinc in the body's cells, enabling researchers to learn more about its functions.Zinc is an essential mineral and is found in every tissue in the body. While the majority of zinc is tightly bound to proteins, tiny amounts are only loosely bound, or "mobile.