Study shows symptoms linked to poor quality of life in long-term childhood cancer survivors
12/16/2013
Due to improved treatments and technologies, more children than ever are surviving cancer. Unfortunately, about 70 percent of these children experience late effects from their disease and treatment 30 years after their cancer diagnosis, which University of Florida Health researchers say significantly impact their quality of life.
New gene-editing system enables large-scale studies of gene function
12/16/2013
Since the completion of the Human Genome Project, which identified nearly 20,000 protein-coding genes, scientists have been trying to decipher the roles of those genes. A new approach developed at MIT, the Broad Institute, and the Whitehead Institute should speed up the process by allowing researchers to study the entire genome at once.
Patients newly diagnosed with advanced breast cancer and a solitary bone metastasis could benefit from surgery prior to other treatment, according to early results from a first-of-its kind clinical trial presented at the 2013 San Antonio Breast Cancer Symposium."In the U.S.
Systems medicine paves the way for improved treatment for leukemia patients
12/16/2013
A multi-disciplinary team of researchers at the Institute for Molecular Medicine Finland, FIMM, and the Helsinki University Central Hospital has developed a novel individualized systems medicine (ISM) strategy which enables selection of potentially effective cancer therapies for individual patients.
Cancer diagnosis more likely to limit careers for patients from rural areas
12/16/2013
Compared to their counterparts in cities, cancer patients living in rural areas tend to retire early after being diagnosed, and are less likely to go on paid disability leave while receiving treatment.
Altitude training: athletes 'only benefit at certain heights'
12/16/2013
Exposure to high altitudes has been long believed to benefit athletes during training. The higher the altitude, the less oxygen there is, meaning the body works harder to increase its oxygen levels. It is thought this process can lead to better athletic performance, but it has been unclear as to which altitude height is the most beneficial - until now.
Helping cancer researchers make sense of the deluge of genetic data
12/16/2013
A newly improved internet research tool is helping cancer researchers and physicians make sense out of a deluge of genetic data from nearly 100,000 patients and more than 50,000 mice.The tool, called the Gene Expression Barcode 3.
SAN ANTONIO, TX - The oral mammalian target of rapamycin inhibitor everolimus combined with the steroidal aromatase inhibitor exemestane significantly improves the overall response rate in postmenopausal women with advanced breast cancer, according to data released at the 37th Annual San Antonio Breast Cancer Symposium (SABCS).
New models of drug-resistant breast cancer point to better treatments
12/16/2013
Human breast tumors transplanted into mice are excellent models of metastatic cancer and are providing insights into how to attack breast cancers that no longer respond to the drugs used to treat them, according to research from Washington University School of Medicine in St. Louis.
Deep sequencing of breast cancer tumors to predict clinical outcomes after single dose of therapy
12/16/2013
New research from University Hospitals (UH) Case Medical Center Seidman Cancer Center and Case Comprehensive Cancer Center at Case Western Reserve University examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.