Regulation of Cancer-Causing Protein Could Lead to New Therapeutic Targets
12/20/2013
Researchers with the Cincinnati Cancer Center (CCC) and the University of Cincinnati Cancer Institute have discovered a new regulation for the cancer-causing protein KRas which may help with the development of targeted therapies for patients with a KRas mutation.
Continuing decrease in deaths from lung cancer
12/20/2013
The Annual Report to the Nation on the Status of Cancer, covering the period 1975-2010, showed death rates for lung cancer, which accounts for more than one in four cancer deaths, dropping at a faster pace than in previous years.
New therapies for cancer likely following discovery of ancient chemical bond
12/20/2013
A chemical bond discovered by Vanderbilt University scientists that is essential for animal life and which hastened the "dawn of the animal kingdom" could lead to new therapies for cancer and other diseases.The report, published online by the Proceedings of the National Academy of Sciences(PNAS), was co-authored by 83 participants in the "Aspirnaut" K-20 STEM pipeline program for diversity.
Promising results for personalized brain tumor vaccine
12/19/2013
New research details an experimental vaccine that could help improve the survival of patients with a lethal brain tumor called glioblastoma mutiforme, compared with standard care alone. This is according to a study published in the journal Neuro-Oncology.
Scientists unlock prostate cancer protein in move which could lead to improved cancer vaccines
12/19/2013
UK scientists have identified how a specific region of a prostate-related protein can be used to trigger the body's immune response against prostate cancer. The study by scientists at Nottingham Trent University - and published in the European Journal of Immunology - could pave the way for new and improved vaccines for prostate cancer.
Breast surgeons report improved visualization of treatment area for radiation therapy
12/19/2013
The BioZorb™ three-dimensional surgical marker dramatically improves visualization of the treatment area for radiation planning and therapy, according to a presentation at the prestigious San Antonio Breast Cancer Symposium 2013. The scientific poster reports that the tissue marker is easy to place, safe to use and well tolerated by patients.
DNA unravels in aging cells
12/19/2013
Senescent cells, which are metabolically active but no longer capable of dividing, contribute to aging, and senescence is a key mechanism for preventing the spread of cancer cells. A study in The Journal of Cell Biology identifies a common, early marker of senescent cells that could have important implications for tumor suppression and aging-related diseases like Progeria.
Blocking tumor-associated macrophages decreased glioblastoma's growth & extended survival in mice
12/19/2013
An experimental drug that targets macrophages, a type of immune cell, in the microenvironment surrounding the lethal brain tumor glioblastoma multiforme decreased the cancer's growth and extended survival of laboratory mice with the cancer, scientists reported at the American Society for Cell Biology (ASCB) annual meeting in New Orleans.
Spontaneous fusion with macrophages empowers cancer cells to spread
12/19/2013
Cancer cells that spontaneously fuse with macrophages, the immune system's healthy scavenger cells, play a key role in the metastasis, or spread of the cancer to other areas of the body, according to research presented at the American Society for Cell Biology annual meeting in New Orleans.The researchers, Alain Silk, Ph.D., Melissa Wong, Ph.D.
For women with chemo-resistant breast cancer, bisphosphonate treatment fails to improve outcomes
12/19/2013
Treatment with the bisphosphonate zoledronate did not improve outcomes for women with chemoresistant breast cancer, according to initial results of a phase III clinical trial presented at the 2013 San Antonio Breast Cancer Symposium.Many patients with breast cancer are treated with chemotherapy prior to surgery.