Nomogram aims to enable informed decision-making and personalized treatment for prostate cancer
1/14/2014
Studies have found that prostate cancer is overdiagnosed in up to 42 percent of cases, prompting men to receive unnecessary treatment that can cause devastating side effects, including impotence and incontinence.
Lymphoma drug protects against type 1 diabetes
1/14/2014
New research shows that low doses of a cancer drug protect against the development of type 1 diabetes in mice. At the same time, the medicine protects the insulin-producing cells from being destroyed.
Anti-cancer properties of diabetes drug 'should be re-evaluated'
1/14/2014
Many clinical trials have looked to the use of metformin - a drug already used to treat diabetes - as a way of suppressing tumor growth in cancer by activating a molecule called AMP-activated protein kinase. But new research suggests that activation of this molecule may actually encourage tumor growth.
Improving understanding of RNA using powerful new technique
1/14/2014
Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.
New target discovered for brain cancer treatment
1/14/2014
A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme (GBM), the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.
Minority and poor patients diagnosed with more advanced thyroid cancers
1/14/2014
UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets.
During clotting red blood cells become shape shifters
1/14/2014
Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types, transforming - among many other forms - into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself. While studying how blood clots contract John W. Weisel, Ph.D.
Infection-fighting cellular process 'a cause of childhood leukemia'
1/13/2014
The American Cancer Society states that leukemia is the most common cancer in children and teens in the US, accounting for 1 in 3 cancers. Now, researchers have found that a cellular mechanism that fights off infection may contribute to the development of the disease in youngsters, opening doors for further research into treatment for the condition.
GlaxoSmithKline plc has announced that the U.S. Food and Drug Administration (FDA) has approved Mekinist® (trametinib) for use in combination with Tafinlar® (dabrafenib) for the treatment of patients with unresectable melanoma (melanoma that cannot be removed by surgery) or metastatic melanoma (melanoma which has spread to other parts of the body) with BRAF V600E or V600K mutations.
BerGenBio presents data at AACR-ISLAC conference on the molecular origins of lung cancer
1/13/2014
BerGenBio AS, an oncology biopharmaceutical company, announces that preclinical data demonstrating that its lead compound, BGB324 has potential application as a novel treatment for non-small cell lung cancer (NSCLC) was presented in a poster at the American Association of Cancer Research and The International Association for the Study of Lung Cancer's (AACR-ISLAC) joint conference on the...