Cervical cancer: the importance of regular screening
1/15/2014
The American Cancer Society states that cervical cancer used to be the leading cause of cancer death for women in the US. But because more women are undergoing screening for the disease, the number of deaths from the condition have decreased significantly over the past 40 years.
When Homo sapiens left Africa and had to adapt to less sunny climates, there was a mutation in one of the genes responsible for regulating the synthesis of melanin, the MC1R gene, which involved a discoloration of the skin. This discoloration allowed for better absorption of vitamin D, necessary for growth, but it also increased the risk of developing skin cancer in adulthood.
Test for early diagnosis of lung cancer subject of new Journal of Clinical Oncology paper
1/15/2014
GENSIGNIA Ltd, a London-based privately held molecular diagnostics company with laboratory operations in San Diego, CA and Fondazione IRCCS, Istituto Nazionale dei Tumori (INT), Milan, a National Cancer Research Center in Italy, has announced that positive clinical validation results for the microRNA signature classifier (MSC) Lung Cancer assay were published in the Journal of Clinical Oncology...
New horizons in radiotherapy?
1/15/2014
Targeted radiation therapy that is less harmful to healthy cells could see the light of day thanks to a team of French researchers from the Laboratoire de Chimie Physique - Matière et Rayonnement (CNRS/UPMC) working in collaboration with German and American scientists...
Test for early diagnosis of lung cancer subject of new Journal of Clinical Oncology paper
1/15/2014
GENSIGNIA Ltd, a London-based privately held molecular diagnostics company with laboratory operations in San Diego, CA and Fondazione IRCCS, Istituto Nazionale dei Tumori (INT), Milan, a National Cancer Research Center in Italy, has announced that positive clinical validation results for the microRNA signature classifier (MSC) Lung Cancer assay were published in the Journal of Clinical Oncology...
Discovery of genetic diversity within multiple myeloma tumors could have implications for treatment
1/15/2014
The most comprehensive genetic study to date of the blood cancer multiple myeloma has revealed that the genetic landscape of the disease may be more complicated than previously thought. Through results published in Cancer Cell, a team of Broad researchers has shown that an individual patient's tumor can harbor populations of cancer cells equipped with different mutations.
Link between immune system development and leukemia
1/15/2014
Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia.Acute lymphoblastic leukaemia or ALL is the most common form of childhood leukaemia. A key factor driving this leukaemia for one in four ALL patients is a mutation that causes two of their genes, ETV6 and RUNX1, to fuse together.
Growing artificial bone marrow
1/15/2014
Artificial bone marrow may be used to reproduce hematopoietic stem cells. A prototype has now been developed by scientists of KIT, the Max Planck Institute for Intelligent Systems, Stuttgart, and Tubingen University. The porous structure possesses essential properties of natural bone marrow and can be used for the reproduction of stem cells at the laboratory.
Regorafenib: hint of minor added benefit
1/15/2014
Advantage in overall survival, but disadvantage in severe side effectsRegorafenib (trade name: Stivarga) has been approved in Germany since August 2013 for adults with metastatic colorectal cancer in whom previous treatments are no longer effective or for whom these alternatives are not an option.
Patients with cancers of the head and neck who received intensity-modulated radiation therapy (IMRT) - a technology designed to more precisely target cancer cells and spare nearby tissue - experienced improved outcomes, as well as reduced toxicities, compared to patients receiving conventional radiation therapy, according to new research from The University of Texas MD Anderson Cancer Center.