Key mechanisms found to inhibit metastasis of deadly "triple negative" breast cancers
1/20/2014
A team of researchers from the Cleveland Clinic and Case Western Reserve School of Medicine have identified critical complex mechanisms involved in the metastasis of deadly "triple negative" breast cancers (TNBC). These tumors are extremely difficult to treat, frequently return after remission, and are the most aggressive form of breast cancer in women.
Vitamin B3, fiber 'protects against colon cancer and inflammation'
1/20/2014
Previous research has suggested that a diet rich in fiber may reduce the risk of colon inflammation and cancer. But new research suggests that niacin, also known as vitamin B3, may also help protect against these conditions.The research team, including co-author Dr.
Monoclonal antibody therapy enhances removal of circulating tumor cells
1/20/2014
Monoclonal antibodies directed against tumor antigens have proven effective for treating some forms of cancer. Despite the increasing use of monoclonal antibody therapy, it is not clear how these antibodies drive tumor removal.
Vitamin B3, fiber 'protects against colon cancer and inflammation'
1/20/2014
Previous research has suggested that a diet rich in fiber may reduce the risk of colon inflammation and cancer. But new research suggests that niacin, also known as vitamin B3, may also help protect against these conditions.The research team, including co-author Dr.
At a glance, DNA is a rather simple sequence of A, G, C, T bases, but once it is packaged by histone proteins into an amalgam called chromatin, a more complex picture emerges. Histones, which come in four subtypes - H2A, H2B, H3, and H4 - can either coil DNA into inaccessible silent regions or untwist it to allow gene expression.
Promising results of phase II trial of Bevacizumab (Avastin) in locally advanced cervical cancer
1/19/2014
An article published in the January issue of the International Journal of Radiation Oncology, Biology and Physics reports results of the Radiation Therapy Oncology Group (RTOG) phase II clinical trial of Bevacizumab (Avastin) in addition to cisplatin and pelvic radiation for locally advanced cervical cancer.
Coevolution between humans and bacteria found to reduce gastric cancer risk
1/19/2014
Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person's risk of disease. Working with colleagues in Columbia and the U.S.
Fewer years of life lost to cancer
1/19/2014
Since the enactment of the National Cancer Act in 1971, the U.S. has spent hundreds of billions of dollars in cancer research and treatment. And yet, the cancer mortality rate - the historic benchmark of progress - has only declined modestly while the mortality rates of other leading causes of death have declined substantially.
Promising results of phase II trial of Bevacizumab (Avastin) in locally advanced cervical cancer
1/19/2014
An article published in the January issue of the International Journal of Radiation Oncology, Biology and Physics reports results of the Radiation Therapy Oncology Group (RTOG) phase II clinical trial of Bevacizumab (Avastin) in addition to cisplatin and pelvic radiation for locally advanced cervical cancer.
Clarifying mode of action of a targeted treatment for leukemia
1/18/2014
The mechanism of senescence - or premature cell ageing - can have an anticancer effect. This new work, conducted by Hugues de Thé and his team (Paris Diderot University/ Inserm/ CNRS/ AP-HP), was published in Nature Medicine.