Breast cancer drug improves outcomes for some bladder cancer patients
1/24/2014
Researchers at Mayo Clinic have found amplification of HER2, a known driver of some breast cancers, in a type of bladder cancer called micropapillary urothelial carcinoma (MPUC) and have shown that the presence of HER2 amplification is associated with particularly aggressive tumors.
Outcome in HPV-related oral cancers not necessarily predicted by number of cancer stem cells
1/24/2014
New research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that it may be the quality of cancer stem cells rather than their quantity that leads to better survival in certain patients with oral cancer.
Folic acid linked to breast cancer growth in animal study
1/23/2014
Folic acid is a well-known supplement to many women, particularly those who are or plan to be pregnant. But a new study suggests that taking large amounts of folate - a B vitamin - and its synthetic form, folic acid, might actually increase the risk of developing breast cancer.
Inherited gene mutations found in 20% of women with ovarian cancer
1/23/2014
Genetic studies of inherited predisposition to ovarian cancer have tended to focus on women with a known family history of the disease. Now, a new study of ovarian cancer patients with no known family history of the disease found one fifth of them had inherited alterations in genes known to be linked to ovarian and breast cancer.
Breast cancer in young women after treatment for Hodgkin's disease during childhood or adolescence
1/23/2014
Girls treated for Hodgkin's disease during adolescence acquire a considerable risk of developing breast cancer, as shown by an observational study published in the current issue of Deutsches Ärzteblatt International.
Inherited gene mutations found in 20% of women with ovarian cancer
1/23/2014
Genetic studies of inherited predisposition to ovarian cancer have tended to focus on women with a known family history of the disease. Now, a new study of ovarian cancer patients with no known family history of the disease found one fifth of them had inherited alterations in genes known to be linked to ovarian and breast cancer.
Acute myeloid leukemia may be initiated by single mutation in bone cells
1/23/2014
Acute myeloid leukemia (AML) is a blood cancer, but for many patients the cancer may originate from an unusual source: a mutation in their bone cells.In a study published in the online edition of Nature, researchers at Columbia University Medical Center (CUMC) found that a mutation in the bone cells called osteoblasts, which build new bone, causes AML in mice.
Potential new target in Ewing's Sarcoma
1/23/2014
Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this fusion has to date proven very difficult.
Cancer diagnosis doesn't increase a child's risk of post-traumatic stress disorder
1/23/2014
A St. Jude Children's Research Hospital study found that despite being diagnosed with life-threatening illnesses, childhood cancer patients are no more likely than their healthy peers to develop post-traumatic stress disorder (PTSD). The research appears in the current online edition of the Journal of Clinical Oncology.
Longer screening intervals possible with HPV-based tests
1/22/2014
A new study from Karolinska Institutet in Sweden finds that testing for human papilloma virus (HPV) allows for longer time between screening tests when compared to cytology-based testing. The study is published in the scientific journal British Medical Journal (BMJ).Cervical screening programs have until recently relied on cytology to identify women at risk for developing cervical cancer.