Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25 percent
1/28/2014
A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than previously thought. By analyzing the genomes of thousands of patients' tumors, a Broad Institute-led research team has discovered many new cancer genes - expanding the list of known genes tied to these cancers by 25 percent.
Many internists don't feel equipped to manage care of adults who had cancer as children
1/28/2014
A recent study shows that many internists feel ill-equipped to care for adult patients who are childhood cancer survivors. Eugene Suh, MD, assistant professor in the division of Pediatric Hematology & Oncology at Loyola University Chicago Stritch School of Medicine, was first author of the study that was conducted the University of Chicago with Tara Henderson, MD, MPH.
Possible link identified between hereditary cancer genes and increased risk of cancer from alcohol
1/28/2014
In laboratory experiments conducted on human cell lines at the Johns Hopkins Kimmel Cancer Center, scientists have shown that people carrying certain mutations in two hereditary cancer genes, BRCA2 and PALB2, may have a higher than usual susceptibility to DNA damage caused by a byproduct of alcohol, called acetaldehyde.
Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25 percent
1/28/2014
A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than previously thought. By analyzing the genomes of thousands of patients' tumors, a Broad Institute-led research team has discovered many new cancer genes - expanding the list of known genes tied to these cancers by 25 percent.
Exhaled breath may help identify early lung cancer
1/28/2014
Specific compounds found in exhaled breath may help diagnose lung cancer in its early stages, according to a study released at the 50th Annual Meeting of The Society of Thoracic Surgeons. The discovery was made when Michael Bousamra, MD and researchers from the University of Louisville examined patients with suspicious lung lesions.
Growth of vestibular schwannomas/acoustic neuromas may be halted by aspirin
1/28/2014
Researchers from Massachusetts Eye and Ear, Harvard Medical School, Massachusetts Institute of Technology and Massachusetts General Hospital have demonstrated, for the first time, that aspirin intake correlates with halted growth of vestibular schwannomas (also known as acoustic neuromas), a sometimes lethal intracranial tumor that typically causes hearing loss and tinnitus.
Second breast cancers may be prevented by moderate doses of radiation therapy to unaffected breast
1/28/2014
Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast.
Exhaled breath may help identify early lung cancer
1/28/2014
Specific compounds found in exhaled breath may help diagnose lung cancer in its early stages, according to a study released at the 50th Annual Meeting of The Society of Thoracic Surgeons. The discovery was made when Michael Bousamra, MD and researchers from the University of Louisville examined patients with suspicious lung lesions.
Researchers discover new hormone receptors to target when treating breast cancer
1/27/2014
About three-quarters of breast cancers, the most common cancer in women in the U.S., are estrogen hormone dependent. Patients with this type of breast cancer are initially treated with drugs that block estrogen, such as Tamoxifen. However, one-third to half of these patients eventually become resistant to this treatment.
Long-living breast stem cells give clues to cancer cells of origin
1/27/2014
Researchers in Australia have found that breast stem cells and their "daughters" have a longer life than previously believed. This newly discovered longer lifespan suggests that these cells could carry damage or genetic defects earlier in life that eventually lead to cancer decades later.