Stem cells and cancer cells kept in place by nuclear stiffness
2/28/2014
Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus' DNA compared to a stiffer nucleus.
Spread of breast cancer cells less likely when one gene is turned off
2/28/2014
New research suggests that a protein only recently linked to cancer has a significant effect on the risk that breast cancer will spread, and that lowering the protein's level in cell cultures and mice reduces chances for the disease to extend beyond the initial tumor.
Personalized treatment approach may be best for second-most common breast cancer subtype
2/28/2014
The second-most common type of breast cancer is a very different disease than the most common and appears to be a good candidate for a personalized approach to treatment, according to a multidisciplinary team led by University of Pittsburgh Cancer Institute (UPCI) scientists.
Study helps explain chronic inflammation in autoimmunity and cancer
2/28/2014
Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the journal Science Translational Medicine.
Spread of breast cancer cells less likely when one gene is turned off
2/28/2014
New research suggests that a protein only recently linked to cancer has a significant effect on the risk that breast cancer will spread, and that lowering the protein's level in cell cultures and mice reduces chances for the disease to extend beyond the initial tumor.
Personalized treatment approach may be best for second-most common breast cancer subtype
2/28/2014
The second-most common type of breast cancer is a very different disease than the most common and appears to be a good candidate for a personalized approach to treatment, according to a multidisciplinary team led by University of Pittsburgh Cancer Institute (UPCI) scientists.
Mailing free test kits improves colon cancer screening rates
2/27/2014
Colon cancer screening rates went up by nearly 40% in a Kaiser Permanente study that mailed test kits to patients' homes. The pilot study, funded by the National Institutes of Health (NIH), was part of a program to address disparities among uninsured, low-income and Latino patients. The findings are to be published in the journal BMC Cancer.Lead author Dr.
Mailing free test kits improves colon cancer screening rates
2/27/2014
Colon cancer screening rates went up by nearly 40% in a Kaiser Permanente study that mailed test kits to patients' homes. The pilot study, funded by the National Institutes of Health (NIH), was part of a program to address disparities among uninsured, low-income and Latino patients. The findings are to be published in the journal BMC Cancer.Lead author Dr.
UCLA study finds robotic-assisted prostate surgery offers better cancer control
2/27/2014
An observational study from UCLA's Jonsson Comprehensive Cancer comparing robotic-assisted prostate surgery to open surgery for prostate cancer found that patients who had robotic surgery had fewer instances of cancer cells at the edge of the surgical specimen, or fewer positive margins, and less need of additional cancer treatments, such as hormone therapy or radiation, than patients who had...
Sunburns strike twice
2/27/2014
Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.