New method identifies working copies of genes in human cells; could improve early diagnosis of sick tissues
3/03/2014

In biology, as in real estate, location matters. Working copies of active genes -- called messenger RNAs or mRNAs -- are positioned strategically throughout living tissues, and their location often helps regulate how cells and tissues grow and develop.

Cancer vaccine could use immune system to fight tumors
3/03/2014

Cincinnati Cancer Center (CCC) and UC Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight cancer.

New form of heparin can be deactivated by antidote
3/03/2014

Low-molecular-weight heparin is commonly used in surgeries to prevent dangerous blood clots. But when patients experience the other extreme - uncontrolled bleeding - in response to low-molecular-weight heparin, there is no antidote.

Cancer vaccine could use immune system to fight tumors
3/03/2014

Cincinnati Cancer Center (CCC) and UC Cancer Institute researchers have found that a vaccine, targeting tumors that produce a certain protein and receptor responsible for communication between cells and the body's immune system, could initiate the immune response to fight cancer.

New form of heparin can be deactivated by antidote
3/03/2014

Low-molecular-weight heparin is commonly used in surgeries to prevent dangerous blood clots. But when patients experience the other extreme - uncontrolled bleeding - in response to low-molecular-weight heparin, there is no antidote.

How cancer cells use PARP1 enzyme to resist current therapies could point to next generation of cancer drugs
3/01/2014

In the cells of humans and other organisms, only a subset of genes are active at any given time, depending largely on the stage of life and the particular duties of the cell. Cells use different molecular mechanisms to orchestrate the activation and deactivation of genes as needed.

Fighting cancer with caffeine-based gold compound
3/01/2014

The side effects of ingesting too much caffeine - restlessness, increased heart rate, having trouble sleeping - are well known, but recent research has shown that the stimulant also has a good side. It can kill cancer cells.

Re-thinking personalized medicine
3/01/2014

As the price for decoding a person's DNA keeps dropping, expectations for personalized medicine based on specific genetic profiling rise. But translating an individual's genetic data into finely tailored medical treatments still faces major challenges, explains a new article in Chemical & Engineering News (C&EN;), the weekly magazine of the American Chemical Society.

Fighting cancer with caffeine-based gold compound
3/01/2014

The side effects of ingesting too much caffeine - restlessness, increased heart rate, having trouble sleeping - are well known, but recent research has shown that the stimulant also has a good side. It can kill cancer cells.

VTT's hyperspectral camera shows promising results in detection of skin field cancerization
2/28/2014

VTT Technical Research Centre of Finland has developed a lightweight, handheld, ultra-precision hyperspectral camera for the detection of skin cancers and their precursors. From the surface of the skin, the camera recognises early stages of cancer that are invisible to the naked eye.