Epigenetics and oral health
3/10/2014
A visit to the dentist could one day require a detailed look at how genes in a patient's body are being switched on or off, as well as examining their pearly whites, according to researchers at the University of Adelaide.
Identification of gene important to breast development and breast cancer
3/10/2014
Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.In cancer, normal cells can become unpredictable or aggressive and thus difficult to treat with anti-cancer drugs. This is especially true in breast cancer.
Target identified for shutting down growth of prostate cancer cells
3/10/2014
Scientists at UT Southwestern Medical Center have identified an important step toward potentially shutting down the growth of prostate cancer cells.Dr. Ralf Kittler, Assistant Professor of Pharmacology, studies ERG, a protein that facilitates the transformation of normal prostate cells into cancer cells.
In zebrafish model, common mutation is culprit in acute leukemia relapse
3/10/2014
Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse. The research, published in Cancer Cell, could translate into improved patient care strategies for this particular blood cancer, which typically affects children but is more deadly in adults.
Targeted drug 'prolongs survival for cervical cancer patients'
3/10/2014
The American Cancer Society estimate that there will be 12,360 new cases of invasive cervical cancer diagnosed this year, with 4,020 deaths from the disease. Now, a phase II trial has found that a targeted antitumor drug could prolong the survival of women with cervical cancer.The research team, led by Dr.
Where does 'hidden fat' come from?
3/10/2014
It is now common knowledge that having too much fat is bad for you, but less well known is the serious threat posed by the "hidden fat" that surrounds our vital organs. New research published in the journal Nature Cell Biology claims to have discovered where this hidden, or "visceral fat," comes from.Visceral fat and subcutaneous fat are the two main types of fat in the body.
Study helps refine personalized approach to breast cancer diagnosis and treatment
3/10/2014
A method called molecular subtyping can help doctors better determine which of their breast cancer patients are at high risk of getting breast cancer again, a new study led by the University of South Florida reports.
Iron deficiency important to assess in children adopted from institutional settings
3/10/2014
Iron deficiency predicts lower IQ scores and poor higher-order thinking skills in children adopted from institutional settings like orphanages, according to a new longitudinal study.The study analyzed data on 55 children adopted from international institutions, with a focus on nutritional status.
A Ludwig Cancer Research study suggests that the clinical efficacy of checkpoint blockade, a powerful new strategy to harness the immune response to treat cancers, might be dramatically improved if combined with oncolytic virotherapy, an investigational intervention that employs viruses to destroy tumors.
A Ludwig Cancer Research study suggests that the clinical efficacy of checkpoint blockade, a powerful new strategy to harness the immune response to treat cancers, might be dramatically improved if combined with oncolytic virotherapy, an investigational intervention that employs viruses to destroy tumors.