Some chemotherapy drugs induce hyper proliferation in stem cells that could lead to tumor recurrence
3/12/2014
Using a new approach to systematically test chemotherapy drugs in an unusual animal model, a research team led by University of Massachusetts Amherst molecular biologist Michele Markstein, with Norbert Perrimon at Harvard Medical School, report that several have a serious side effect: Inducing hyper proliferation in stem cells that could lead to tumor recurrence.
Personalized treatment prolongs the life of lung cancer patients
3/11/2014
The National Cancer Institute (INCan) has progressed from a rate of nine months of survival to 30 with personalized treatments for patients diagnosed with lung cancer in metastatic stage, i.e., when the disease has spread to different parts of the body.
New approach needed to prostate cancer screening
3/11/2014
The UK needs to invest in testing for those men most at risk of prostate cancer rather than follow a cast-the-net-wide approach targeting the whole population, a leading scientist from The University of Manchester - part of Manchester Cancer Research Centre - has argued at an international conference.
Stem cell study opens door to undiscovered world of biology
3/11/2014
For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells - something scientists have long struggled to accomplish.
Researchers at the UNC School of Medicine have devised a new biochemical technique that will allow them and other scientists to delve much deeper than ever before into the specific cellular circuitry that keeps us healthy or causes disease.
Cells appearing normal may actually be harbingers of lung cancer
3/11/2014
Seemingly healthy cells may in fact hide clues that lung cancer will later develop, according to a study led by researchers at The University of Texas MD Anderson Cancer Center The research is published online in the Journal of the National Cancer Institute.
Risk for ovarian cancer increased by being overweight or obese
3/11/2014
Body weight is not a factor that has been widely associated with the the risk of developing ovarian cancer. But new research suggests that women who are overweight or obese are more likely to develop the disease, compared with women of a healthy weight.
Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found. Their study, published online in the Journal of the National Cancer Institute, also found that the markers identified a small group of patients who responded to the investigational drug atrasentan.
Being overweight or obese 'a risk factor' for ovarian cancer
3/11/2014
Body weight is not a factor that has been widely associated with the the risk of developing ovarian cancer. But new research suggests that women who are overweight or obese are more likely to develop the disease, compared with women of a healthy weight.
New hope in the battle against glioblastoma offered by anti-psychotic medications
3/11/2014
Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in the online edition of Oncotarget.The team of scientists, led by principal investigator, Clark C.